Making waves: New developments in toxicology with the zebrafish

KA Horzmann, JL Freeman - Toxicological Sciences, 2018 - academic.oup.com
The laboratory zebrafish (Danio rerio) is now an accepted model in toxicologic research.
The zebrafish model fills a niche between in vitro models and mammalian biomedical …

Advancements in zebrafish applications for 21st century toxicology

GR Garcia, PD Noyes, RL Tanguay - Pharmacology & therapeutics, 2016 - Elsevier
The zebrafish model is the only available high-throughput vertebrate assessment system,
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …

An expanding role for nonvisual opsins in extraocular light sensing physiology

M Andrabi, BA Upton, RA Lang… - Annual review of vision …, 2023 - annualreviews.org
We live on a planet that is bathed in daily and seasonal sunlight cycles. In this context,
terrestrial life forms have evolved mechanisms that directly harness light energy (plants) or …

Zebrafish behavior: opportunities and challenges

MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

Approaches to test the neurotoxicity of environmental contaminants in the zebrafish model: from behavior to molecular mechanisms

JA Fitzgerald, S Könemann… - Environmental …, 2021 - academic.oup.com
The occurrence of neuroactive chemicals in the aquatic environment is on the rise and
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …

Advanced morphological—behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and …

PD Noyes, DE Haggard, GD Gonnerman… - Toxicological …, 2015 - academic.oup.com
The increased use of flammable plastics and electronic devices along with stricter fire safety
standards has led to the heavy use of flame retardant chemicals in many consumer …

[HTML][HTML] Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior

R Portugues, CE Feierstein, F Engert, MB Orger - Neuron, 2014 - cell.com
Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …

Effects of developmental exposure to individual and combined PFAS on development and behavioral stress responses in larval zebrafish

M Hamed, A Vats, IE Lim, B Sapkota… - Environmental …, 2024 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals known for their
widespread use and persistence in the environment. Laboratory and epidemiological …

The €100 lab: A 3D-printable open-source platform for fluorescence microscopy, optogenetics, and accurate temperature control during behaviour of zebrafish, Drosophila, and …

A Maia Chagas, LL Prieto-Godino, AB Arrenberg… - PLoS …, 2017 - journals.plos.org
Small, genetically tractable species such as larval zebrafish, Drosophila, or Caenorhabditis
elegans have become key model organisms in modern neuroscience. In addition to their low …

[HTML][HTML] Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish

L Truong, Y Rericha, P Thunga, S Marvel… - Journal of hazardous …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are a class of widely used chemicals with limited
human health effects data relative to the diversity of structures manufactured. To help fill this …