Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

Recently, diverse functional materials that take subcellular structures as therapeutic targets
are playing increasingly important roles in cancer therapy. Here, particular emphasis is …

Single-atom nanozymes (SAzymes), with individually isolated metal atom as active sites,
have shown tremendous potential as enzyme-based drugs for enzymatic therapy. However …

Elevated levels of reactive oxygen species (ROS) have commonly been implicated in a
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …

Metastatic cancer is difficult to cure because of its uncontrollable nature and side effects
during treatment. We constructed a reactive oxygen species (ROS)‐activated smart …

Simple Summary Cancer cells are consistently under oxidative stress, as reflected by
elevated basal level of reactive oxygen species (ROS), due to increased metabolism driven …

Tumor therapeutic efficacy is determined, to a great extent, by the delivery efficiency of
therapeutic drugs to their final targets. The cell nucleus has been proven to be the main …

Though numerous external‐stimuli‐triggered tumor therapies, including phototherapy,
radiotherapy, and sonodynamic therapy have made great progress in cancer therapy, the …

The hypoxic tumor microenvironment severely lowers the therapeutic efficacy of oxygen-
dependent anticancer modalities because tumor hypoxia hinders the generation of toxic …

The ultimate goal of cancer therapy is to eliminate malignant tumors while causing no
damage to normal tissues. In the past decades, numerous nanoagents have been employed …