Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Plasmids are mobile genetics elements that play an important role in the environmental
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …

Motivation: Plasmids are stably maintained extra-chromosomal genetic elements that
replicate independently from the host cell's chromosomes. Although plasmids harbor …

Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

To benchmark algorithms for automated plasmid sequence reconstruction from short-read
sequencing data, we selected 42 publicly available complete bacterial genome sequences …

Third-generation cephalosporins are a class of β-lactam antibiotics that are often used for
the treatment of human infections caused by Gram-negative bacteria, especially Escherichia …

Conjugation is a contact-dependent mechanism for the transfer of plasmid DNA between
bacterial cells, which contributes to the dissemination of antibiotic resistance. Here, we use …