Structural and functional characterisation of cardiac fibroblasts
Cardiac fibroblasts form one of the largest cell populations, in terms of cell numbers, in the
heart. They contribute to structural, biochemical, mechanical and electrical properties of the …
heart. They contribute to structural, biochemical, mechanical and electrical properties of the …
Cardiac fibroblasts: friend or foe?
TA Baudino, W Carver, W Giles… - American Journal of …, 2006 - journals.physiology.org
Cardiac function is determined by the dynamic interaction of various cell types and the
extracellular matrix that composes the heart. This interaction varies with the stage of …
extracellular matrix that composes the heart. This interaction varies with the stage of …
Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture
The heart is a muscular organ with a wrap**, laminar structure embedded with neural and
vascular networks, collagen fibrils, fibroblasts, and cardiac myocytes that facilitate …
vascular networks, collagen fibrils, fibroblasts, and cardiac myocytes that facilitate …
Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems
Abstract Development of cardiac fibrosis and arrhythmias is controlled by the activity of and
communication between cardiomyocytes and fibroblasts in the heart. Myocyte-fibroblast …
communication between cardiomyocytes and fibroblasts in the heart. Myocyte-fibroblast …
The effect of immobilized RGD peptide in alginate scaffolds on cardiac tissue engineering
Cardiac tissue engineering aims to regenerate damaged myocardial tissues by applying
heart patches created in vitro. The present study was undertaken to explore the possible role …
heart patches created in vitro. The present study was undertaken to explore the possible role …
[HTML][HTML] Fibroblast–myocyte electrotonic coupling: does it occur in native cardiac tissue?
Heterocellular electrotonic coupling between cardiac myocytes and non-excitable
connective tissue cells has been a long-established and well-researched fact in vitro …
connective tissue cells has been a long-established and well-researched fact in vitro …
Sarcomere alignment is regulated by myocyte shape
Cardiac organogenesis and pathogenesis are both characterized by changes in myocyte
shape, cytoskeletal architecture, and the extracellular matrix (ECM). However, the …
shape, cytoskeletal architecture, and the extracellular matrix (ECM). However, the …
Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation
Myocytes, while giving rise to the bulk volume of normal cardiac muscle, form a “minority cell
population” in the heart compared with nonmyocytes, chiefly fibroblasts. The heterogeneous …
population” in the heart compared with nonmyocytes, chiefly fibroblasts. The heterogeneous …
Are interactions between epicardial adipose tissue, cardiac fibroblasts and cardiac myocytes instrumental in atrial fibrosis and atrial fibrillation?
A Krishnan, E Chilton, J Raman, P Saxena… - Cells, 2021 - mdpi.com
Atrial fibrillation is very common among the elderly and/or obese. While myocardial fibrosis
is associated with atrial fibrillation, the exact mechanisms within atrial myocytes and …
is associated with atrial fibrillation, the exact mechanisms within atrial myocytes and …
Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical …
Recent interest has focused on the importance of the nucleus and associated
nucleoskeleton in regulating changes in cardiac gene expression in response to …
nucleoskeleton in regulating changes in cardiac gene expression in response to …