Surveying membrane landscapes: a new look at the bacterial cell surface
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …
Molecular Machines that Facilitate Bacterial Outer Membrane Protein Biogenesis
Almost all outer membrane proteins (OMPs) in Gram-negative bacteria contain a β-barrel
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …
The structure of a conserved domain of TamB reveals a hydrophobic β taco fold
The translocation and assembly module (TAM) plays a role in the transport and insertion of
proteins into the bacterial outer membrane. TamB, a component of this system spans the …
proteins into the bacterial outer membrane. TamB, a component of this system spans the …
Bacterial machineries for the assembly of membrane-embedded β-barrel proteins
D Ranava, A Caumont-Sarcos… - FEMS microbiology …, 2018 - academic.oup.com
The outer membrane (OM) of Gram-negative bacteria is an essential organelle that protects
cells from external aggressions and mediates the secretion of virulence factors. Efficient …
cells from external aggressions and mediates the secretion of virulence factors. Efficient …
A noncanonical chaperone interacts with drug efflux pumps during their assembly into bacterial outer membranes
Bacteria have membrane-spanning efflux pumps to secrete toxic compounds ranging from
heavy metal ions to organic chemicals, including antibiotic drugs. The overall architecture of …
heavy metal ions to organic chemicals, including antibiotic drugs. The overall architecture of …
Recent advances in the understanding of trimeric autotransporter adhesins
AR Kiessling, A Malik, A Goldman - Medical Microbiology and Immunology, 2020 - Springer
Adhesion is the initial step in the infection process of gram-negative bacteria. It is usually
followed by the formation of biofilms that serve as a hub for further spread of the infection …
followed by the formation of biofilms that serve as a hub for further spread of the infection …
The TAM: a translocation and assembly module of the β-barrel assembly machinery in bacterial outer membranes
Assembly of proteins into the outer membrane is an essential process in the cell biology of
bacteria. The integration of β-barrel proteins into the outer membrane is mediated by a …
bacteria. The integration of β-barrel proteins into the outer membrane is mediated by a …
The TAM, a Translocation and Assembly Module for protein assembly and potential conduit for phospholipid transfer
The assembly of β-barrel proteins into the bacterial outer membrane is an essential process
enabling the colonization of new environmental niches. The TAM was discovered as a …
enabling the colonization of new environmental niches. The TAM was discovered as a …
Structural basis for substrate selection by the translocation and assembly module of the β‐barrel assembly machinery
RS Bamert, K Lundquist, H Hwang… - Molecular …, 2017 - Wiley Online Library
The assembly of proteins into bacterial outer membranes is a key cellular process that we
are only beginning to understand, mediated by the β‐barrel assembly machinery (BAM) …
are only beginning to understand, mediated by the β‐barrel assembly machinery (BAM) …
The role of host immune cells and Borrelia burgdorferi antigens in the etiology of Lyme disease
D Verhaegh, LAB Joosten, M Oosting - European cytokine network, 2017 - Springer
Lyme disease is a zoonosis caused by infection with bacteria belonging to the Borrelia
burgdorferi species after the bite of an infected tick. Even though an infection by this …
burgdorferi species after the bite of an infected tick. Even though an infection by this …