Integrating organoids and organ-on-a-chip devices

Y Zhao, S Landau, S Okhovatian, C Liu… - Nature Reviews …, 2024 - nature.com
Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that
aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically …

Skeletal muscle differentiation of human iPSCs meets bioengineering strategies: perspectives and challenges

F Iberite, E Gruppioni, L Ricotti - NPJ Regenerative Medicine, 2022 - nature.com
Although skeletal muscle repairs itself following small injuries, genetic diseases or severe
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …

Engineering biomimetic materials for skeletal muscle repair and regeneration

KH Nakayama, M Shayan… - Advanced healthcare …, 2019 - Wiley Online Library
Although skeletal muscle is highly regenerative following injury or disease, endogenous self‐
regeneration is severely impaired in conditions of volume traumatic muscle loss …

Regenerative medicine for skeletal muscle loss: A review of current tissue engineering approaches

B Langridge, M Griffin, PE Butler - Journal of Materials Science: Materials …, 2021 - Springer
Skeletal muscle is capable of regeneration following minor damage, more significant
volumetric muscle loss (VML) however results in permanent functional impairment. Current …

[HTML][HTML] Bioprinting of 3D in vitro skeletal muscle models: A review

P Zhuang, J An, CK Chua, LP Tan - Materials & Design, 2020 - Elsevier
Recent years have witnessed significant progress in skeletal muscle tissue regeneration.
Numerous bioengineering approaches have been implemented to construct in vitro skeletal …

Effects of external stimulators on engineered skeletal muscle tissue maturation

C Mueller, M Trujillo‐Miranda, M Maier… - Advanced Materials …, 2021 - Wiley Online Library
Engineering functional skeletal muscle tissue is an ongoing challenge because of the
complexity of the in vivo microenvironment and the various factors that contribute to the …

Sphingosine 1-phosphate (S1P)/S1P receptor signaling and mechanotransduction: implications for intrinsic tissue repair/regeneration

C Sassoli, F Pierucci, S Zecchi-Orlandini… - International journal of …, 2019 - mdpi.com
Tissue damage, irrespective from the underlying etiology, destroys tissue structure and,
eventually, function. In attempt to achieve a morpho-functional recover of the damaged …

Mechanobiology in tendon, ligament, and skeletal muscle tissue engineering

MTK Bramson, SK Van Houten… - Journal of …, 2021 - asmedigitalcollection.asme.org
Tendon, ligament, and skeletal muscle are highly organized tissues that largely rely on a
hierarchical collagenous matrix to withstand high tensile loads experienced in activities of …

Nanomaterial additives for fabrication of stimuli‐responsive skeletal muscle tissue engineering constructs

AC Farr, KJ Hogan, AG Mikos - Advanced Healthcare Materials, 2020 - Wiley Online Library
Volumetric muscle loss necessitates novel tissue engineering strategies for skeletal muscle
repair, which have traditionally involved cells and extracellular matrix‐mimicking scaffolds …

Impact of crystalline domains on long‐term stability and mechanical performance of anisotropic silk fibroin sponges

EL Aikman, AP Rao, Y Jia, EE Fussell… - … Research Part A, 2024 - Wiley Online Library
Sponge‐like materials made from regenerated silk fibroin biopolymers are a tunable and
advantageous platform for in vitro engineered tissue culture and in vivo tissue regeneration …