Leveraging disulfiram to treat cancer: Mechanisms of action, delivery strategies, and treatment regimens
Y Lu, Q Pan, W Gao, Y Pu, K Luo, B He, Z Gu - Biomaterials, 2022 - Elsevier
Disulfiram (DSF) has been used as an alcoholism drug for 70 years. Recently, it has
attracted increasing attention owing to the distinguished anticancer activity, which can be …
attracted increasing attention owing to the distinguished anticancer activity, which can be …
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients
Nontuberculous mycobacteria (NTM) have recently emerged as important pathogens among
cystic fibrosis (CF) patients worldwide. Mycobacterium abscessus is becoming the most …
cystic fibrosis (CF) patients worldwide. Mycobacterium abscessus is becoming the most …
Epidemic of Postsurgical Infections Caused by Mycobacterium massiliense
RS Duarte, MCS Lourenço, LS Fonseca… - Journal of clinical …, 2009 - Am Soc Microbiol
An epidemic of infections after video-assisted surgery (1,051 possible cases) caused by
rapidly growing mycobacteria (RGM) and involving 63 hospitals in the state of Rio de …
rapidly growing mycobacteria (RGM) and involving 63 hospitals in the state of Rio de …
[HTML][HTML] Alternative therapies against Mycobacterium abscessus infections
I Palucci, G Delogu - Clinical Microbiology and Infection, 2024 - Elsevier
Abstract Background Mycobacterium abscessus (Mab) is considered as the most pathogenic
rapid-growing mycobacteria in humans, causing pulmonary and extra-pulmonary diseases …
rapid-growing mycobacteria in humans, causing pulmonary and extra-pulmonary diseases …
Pipeline of anti‐Mycobacterium abscessus small molecules: Repurposable drugs and promising novel chemical entities
The Mycobacterium abscessus complex is a group of emerging pathogens that are difficult
to treat. There are no effective drugs for successful M. abscessus pulmonary infection …
to treat. There are no effective drugs for successful M. abscessus pulmonary infection …
Modeling nontuberculous mycobacterial infections in zebrafish
The incidence of infections due to nontuberculous mycobacteria (NTM) has increased
rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent …
rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent …
Drug re‐engineering and repurposing: A significant and rapid approach to tuberculosis drug discovery
The prevalence of tuberculosis (TB) remains the leading cause of death from a single
infectious agent, ranking it above all other contagious diseases. The problem to tackle this …
infectious agent, ranking it above all other contagious diseases. The problem to tackle this …
Update on drug-repurposing: is it useful for tackling antimicrobial resistance?
Antimicrobial resistance (AMR) has been globally recognized as a threat to human health
and healthcare systems [1]. In fact, AMR is estimated to be responsible for over 700,000 …
and healthcare systems [1]. In fact, AMR is estimated to be responsible for over 700,000 …
In Vitro and In Vivo Activity of Gepotidacin against Drug-Resistant Mycobacterial Infections
Mycobacterial pathogens, including nontuberculous mycobacteria (NTM) and
Mycobacterium tuberculosis, are pathogens of significant worldwide interest owing to their …
Mycobacterium tuberculosis, are pathogens of significant worldwide interest owing to their …
[HTML][HTML] Disulfiram: A repurposed drug in preclinical and clinical development for the treatment of infectious diseases
MM Custodio, J Sparks, TE Long - Anti-infective agents, 2022 - ncbi.nlm.nih.gov
This article reviews preclinical and clinical studies on the repurposed use of disulfiram
(Antabuse) as an antimicrobial agent. Preclinical research covered on the alcohol sobriety …
(Antabuse) as an antimicrobial agent. Preclinical research covered on the alcohol sobriety …