[HTML][HTML] Natural medicine in neuroprotection for ischemic stroke: Challenges and prospective

T Tao, M Liu, M Chen, Y Luo, C Wang, T Xu… - Pharmacology & …, 2020 - Elsevier
There is a growing interest in using natural medicines to treat stroke as the leading cause of
disability worldwide. Especially plant-derived natural medicines have multiple beneficial …

[HTML][HTML] Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of Embelia ribes Burm.

V Sharma, DNS Gautam, AF Radu, T Behl, SG Bungau… - Antioxidants, 2022 - mdpi.com
Objectives: Embelia ribes Burm.(E. ribes, Myrsinaceae), also known as Vidanga in
Ayurveda, has been shown to have significant therapeutic benefits on several disorders, and …

[HTML][HTML] Formulation and evaluation of mefenamic acid emulgel for topical delivery

R Khullar, D Kumar, N Seth, S Saini - Saudi pharmaceutical journal, 2012 - Elsevier
Emulgels have emerged as a promising drug delivery system for the delivery of hydrophobic
drugs. The objective of the study was to prepare emulgel of mefenamic acid, a NSAID, using …

Zebrafish as a model for epilepsy-induced cognitive dysfunction: a pharmacological, biochemical and behavioral approach

UP Kundap, Y Kumari, I Othman… - Frontiers in …, 2017 - frontiersin.org
Epilepsy is a neuronal disorder allied with distinct neurological and behavioral alterations
characterized by recurrent spontaneous epileptic seizures. Impairment of the cognitive …

Global cerebral ischemia: synaptic and cognitive dysfunction

J T. Neumann, C H. Cohan, K R. Dave… - Current drug …, 2013 - benthamdirect.com
Cardiopulmonary arrest is one of the leading causes of death and disability, primarily
occurring in the aged population. Numerous global cerebral ischemia animal models induce …

Protective Effect of Calendula officinalis L. Flowers Against Monosodium Glutamate Induced Oxidative Stress and Excitotoxic Brain Damage in Rats

BD Shivasharan, P Nagakannan… - Indian Journal of Clinical …, 2013 - Springer
Monosodium glutamate (MSG) is a popular flavour enhancer used in food industries;
however, excess MSG is neurotoxic. Oxidative stress is well documented in MSG induced …

Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats

C Kocak, FE Kocak, R Akcilar, OO Isiklar, H Kocak… - Life sciences, 2016 - Elsevier
Aims Acute myocardial infarction is a serious acute cardiac disorder and heart disease is still
a major public health problem in adults. We investigated the effects of embelin (EMB) and …

Effect of embelin against 3-nitropropionic acid-induced Huntington's disease in rats

SB Dhadde, P Nagakannan, M Roopesh… - Biomedicine & …, 2016 - Elsevier
Nitropropionic acid (3-NP) causes severe neurotoxicity in animals, which depicts
Huntington's disease (HD) in humans. Embelin, the main active constituent of Embelia ribes …

Hyaluronic acid-coated pH sensitive poly (β-amino ester) nanoparticles for co-delivery of embelin and TRAIL plasmid for triple negative breast cancer treatment

Y Xu, D Liu, J Hu, P Ding, M Chen - International Journal of Pharmaceutics, 2020 - Elsevier
Triple negative breast cancer (TNBC) still lacks an effective targeted treatment. In this study,
hyaluronic acid (HA)-mediated tumor targeting and pH-sensitive amphiphilic polymeric …

Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin

AM Schaible, H Traber, V Temml, SM Noha… - Biochemical …, 2013 - Elsevier
Abstract Embelin (2, 5-dihydroxy-3-undecyl-1, 4-benzoquinone) possesses anti-
inflammatory and anti-carcinogenic properties in vivo, and these features have been related …