Fruits are crucial components of a balanced diet and a good source of natural antioxidants,
that have proven efficacy in various chronic illnesses. Various kinds of waste generated from …

Circadian rhythms are∼ 24 h cycles evident in behaviour, physiology and metabolism. The
molecular mechanism directing circadian rhythms is the circadian clock, which is composed …

The improvement of type 2 diabetes mellitus induced by naturally occurring polyphenols,
known as flavonoids, has received considerable attention. However, there is a dearth of …

Diabetes mellitus (DM) is a global health burden that is characterized by the loss or
dysfunction of pancreatic β-cells. In pancreatic β-cells, endoplasmic reticulum (ER) stress is …

Studies suggest heterogeneity in cancer cachexia (CC) among models and biological
sexes, yet examinations comparing models and sexes are scarce. We compared the …

Introduction Nobiletin is a polymethoxyflavonoid abundant in citrus peels and has been
reported to have various bioactive effects. We have previously reported that nobiletin inhibits …

Although diabetes is associated with an increased risk of various diseases, including cancer
and infectious diseases, no definitive cure has yet been found. Long-term treatment for …

Materials and methods A Shiikuwasha extract was dissolved in MediDrop sucralose. Twenty-
four mice were equally divided in three groups and fed with vehicle or low or high dose of …