After malaria, schistosomiasis (or bilharzia) is the second most prevalent disease in Africa,
and is occurring in over 70 countries in tropical and subtropical regions. It is estimated that …

Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as
preventive chemotherapy as part of national helminth control strategies. Given the heavy …

Bilharzia is a parasitic flatworm that causes schistosomiasis, a neglected tropical illness
worldwide. Praziquantel (PZQ) is a commercial single treatment of schistosomiasis so …

Schistosomiasis is a major neglected tropical disease. Control of schistosomiasis currently
relies on a single drug, praziquantel, and despite its efficacy against the all schistosome …

Today schistosomiasis, caused mainly by the three major schistosome species (S. mansoni,
S. haematobium and S. japonicum), has for many decades and still continues to be on a …

Schistosomiasis is a tropical parasitic disease, in which the major clinical manifestation
includes hepatosplenomegaly, portal hypertension, and organs fibrosis. Clinically, treatment …

Drug-resistant pathogens emerge faster than new drugs come out of drug discovery
pipelines. Current and future drug options should therefore be better protected, requiring a …

Schistosomiasis is a debilitating neglected tropical disease caused by schistosome worms.
Global efforts to control schistosomiasis rely predominantly on mass drug administration of …

The main objective of this work is preparation of mesoporous silica nanoparticles loaded
with praziquantel (PZQ-Si) in order to enhance the therapeutic efficacy of praziquantel …

Schistosomiasis is a neglected tropical disease with considerable morbidity. The lone
effective drug, praziquantel (PZQ), is showing emergence of drug resistance hence …