An interleukin 6‐based genetic risk score strengthened with interleukin 10 polymorphisms associated with long‐term kidney allograft outcomes

SK Eskandari, M Gaya da Costa, B Faria… - American Journal of …, 2022 - Wiley Online Library
Of all kidney transplants, half are still lost in the first decade after transplantation. Here, using
genetics, we probed whether interleukin 6 (IL‐6) could be a target in kidney transplantation …

Synergistic impact of three complement polymorphisms in the donor, not the recipient, on long-term kidney allograft survival

F Poppelaars, M Gaya da Costa, B Faria, SK Eskandari… - medRxiv, 2023 - medrxiv.org
Background Genetic analysis in transplantation offers potential for personalized medicine.
Given the crucial role of the complement system in renal allograft injury, we investigated in …