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[HTML][HTML] Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments
Nowadays, diabetes mellitus has emerged as a significant global public health concern with
a remarkable increase in its prevalence. This review article focuses on the definition of …
a remarkable increase in its prevalence. This review article focuses on the definition of …
Emerging targets in type 2 diabetes and diabetic complications
S Demir, PP Nawroth, S Herzig… - Advanced …, 2021 - Wiley Online Library
Type 2 diabetes is a metabolic, chronic disorder characterized by insulin resistance and
elevated blood glucose levels. Although a large drug portfolio exists to keep the blood …
elevated blood glucose levels. Although a large drug portfolio exists to keep the blood …
Genetics of diabetes mellitus and diabetes complications
Diabetes is one of the fastest growing diseases worldwide, projected to affect 693 million
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …
New horizons in diabetic neuropathy: mechanisms, bioenergetics, and pain
Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic
complications create a substantial burden on both the afflicted patients and society as a …
complications create a substantial burden on both the afflicted patients and society as a …
A new look at painful diabetic neuropathy
G Sloan, P Shillo, D Selvarajah, J Wu… - Diabetes research and …, 2018 - Elsevier
The prevalence of diabetes mellitus and its chronic complications continue to increase
alarmingly. Consequently, the massive expenditure on diabetic distal symmetrical …
alarmingly. Consequently, the massive expenditure on diabetic distal symmetrical …
Cardiovascular autonomic neuropathy in diabetes: Pathophysiology, clinical assessment and implications
A Duque, MFF Mediano, A De Lorenzo… - World journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Cardiovascular autonomic neuropathy (CAN) is a debilitating condition that mainly occurs in
long-standing type 2 diabetes patients but can manifest earlier, even before diabetes is …
long-standing type 2 diabetes patients but can manifest earlier, even before diabetes is …
Understanding the role of hyperglycemia and the molecular mechanism associated with diabetic neuropathy and possible therapeutic strategies
Diabetic neuropathy is a neuro-degenerative disorder that encompasses numerous factors
that impact peripheral nerves in the context of diabetes mellitus (DM). Diabetic peripheral …
that impact peripheral nerves in the context of diabetes mellitus (DM). Diabetic peripheral …
Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss
Pathological sensations caused by peripheral painful neuropathy occurring in Type 2
diabetes mellitus (T2DM) are often described as 'sharp'and 'burning'and are commonly …
diabetes mellitus (T2DM) are often described as 'sharp'and 'burning'and are commonly …
Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin‐Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway
Renal interstitial fibrosis is considered to be the typical manifestation of diabetic
nephropathy (DN). Mangiferin has shown positive effect on the prevention or treatment of …
nephropathy (DN). Mangiferin has shown positive effect on the prevention or treatment of …
Diabetes and the risk of sudden cardiac death
Abstract Purpose of Review Persons with diabetes mellitus (DM) have increased morbidity
and mortality rates compared with persons without DM. Sudden cardiac death (SCD) is a …
and mortality rates compared with persons without DM. Sudden cardiac death (SCD) is a …