[PDF][PDF] Drug delivery (nano) platforms for oral and dental applications: tissue regeneration, infection control, and cancer management

P Makvandi, U Josic, M Delfi, F Pinelli… - Advanced …, 2021 - Wiley Online Library
The oral cavity and oropharynx are complex environments that are susceptible to physical,
chemical, and microbiological insults. They are also common sites for pathological and …

Overcoming the rising incidence and evolving mechanisms of antibiotic resistance by novel drug delivery approaches–an overview

CKC Lai, RWY Ng, SSY Leung, M Hui, M Ip - Advanced Drug Delivery …, 2022 - Elsevier
Antimicrobial resistance is a normal evolutionary process for microorganisms. Antibiotics
exerted accelerated selective pressure that hasten bacterial resistance through mutation …

Injectable hydrogels with high drug loading through B–N coordination and ROS-triggered drug release for efficient treatment of chronic periodontitis in diabetic rats

X Zhao, Y Yang, J Yu, R Ding, D Pei, Y Zhang, G He… - Biomaterials, 2022 - Elsevier
The clinical management of chronic periodontitis with diabetes mellitus (CPDM) is a long-
standing thorny issue. The excessive production of reactive oxygen species (ROS) is one of …

Mild hyperthermia-assisted ROS scavenging hydrogels achieve diabetic wound healing

X Qi, X Tong, S You, R Mao, E Cai, W Pan… - ACS Macro …, 2022 - ACS Publications
Excessive reactive oxygen species (ROS) production induces oxidative damage to
biomolecules, which can lead to the development of chronic diseases. Biocompatible …

[HTML][HTML] Recent advances in the development of in situ gelling drug delivery systems for non-parenteral administration routes

B Vigani, S Rossi, G Sandri, MC Bonferoni… - Pharmaceutics, 2020 - mdpi.com
In situ gelling drug delivery systems have gained enormous attention over the last decade.
They are in a sol-state before administration, and they are capable of forming gels in …

Catechol-Modified and MnO2-Nanozyme-Reinforced Hydrogel with Improved Antioxidant and Antibacterial Capacity for Periodontitis Treatment

S Hu, L Wang, J Li, D Li, H Zeng, T Chen… - ACS Biomaterials …, 2023 - ACS Publications
Periodontitis is an inflammatory disease characterized by tooth loss and alveolar bone
resorption. Bacteria are the original cause of periodontitis, and excess reactive oxygen …

Local delivery and controlled release drugs systems: a new approach for the clinical treatment of periodontitis therapy

M Amato, S Santonocito, A Polizzi, GM Tartaglia… - Pharmaceutics, 2023 - mdpi.com
Periodontitis is an inflammatory disease of the gums characterized by the degeneration of
periodontal ligaments, the formation of periodontal pockets, and the resorption of the …

The application of mesoporous silica nanoparticles as a drug delivery vehicle in oral disease treatment

L Fang, H Zhou, L Cheng, Y Wang, F Liu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Mesoporous silica nanoparticles (MSNs) hold promise as safer and more effective
medication delivery vehicles for treating oral disorders. As the drug's delivery system, MSNs …

Local drug delivery systems as therapeutic strategies against periodontitis: A systematic review

Y Wei, Y Deng, S Ma, M Ran, Y Jia, J Meng… - Journal of Controlled …, 2021 - Elsevier
Periodontitis is a chronic inflammation of the soft tissue surrounding and supporting the
teeth, which causes periodontal structural damage, alveolar bone resorption, and even tooth …

Challenges in delivering therapeutic peptides and proteins: A silk-based solution

J Wu, JK Sahoo, Y Li, Q Xu, DL Kaplan - Journal of Controlled Release, 2022 - Elsevier
Peptide-and protein-based therapeutics have drawn significant attention over the past few
decades for the treatment of infectious diseases, genetic disorders, oncology, and many …