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Proteogenomic data and resources for pan-cancer analysis
Summary The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …
Signaling pathways in rheumatoid arthritis: implications for targeted therapy
Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …
progression leads to joint deformity and associated loss of function, which significantly …
The role of microRNAs in neurodegenerative diseases: a review
S Li, Z Lei, T Sun - Cell biology and toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …
regulators in various neuronal degenerative diseases and playact a key role in these …
MIENTURNET: an interactive web tool for microRNA-target enrichment and network-based analysis
Background miRNAs regulate the expression of several genes with one miRNA able to
target multiple genes and with one gene able to be simultaneously targeted by more than …
target multiple genes and with one gene able to be simultaneously targeted by more than …
Liquid biopsies: applications for cancer diagnosis and monitoring
The minimally—or non-invasive detection of circulating tumor-derived components in
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …
The impact of diet on miRNA regulation and its implications for health: a systematic review
The evidence suggests that diet can modulate endogenous microRNA (miRNA) expression.
Changes in miRNA expression may affect metabolic processes and consequently be …
Changes in miRNA expression may affect metabolic processes and consequently be …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation
Y Zhu, C Huang, C Zhang, Y Zhou, E Zhao… - Nature …, 2023 - nature.com
Gastric cancer (GC) is a heterogeneous disease, threatening millions of lives worldwide, yet
the functional roles of long non-coding RNAs (lncRNAs) in different GC subtypes remain …
the functional roles of long non-coding RNAs (lncRNAs) in different GC subtypes remain …
[HTML][HTML] Joint masking and self-supervised strategies for inferring small molecule-miRNA associations
Inferring small molecule-miRNA associations (MMAs) is crucial for revealing the intricacies
of biological processes and disease mechanisms. Deep learning, renowned for its …
of biological processes and disease mechanisms. Deep learning, renowned for its …
Mechanisms of miRNA‐mediated gene regulation from common downregulation to mRNA‐specific upregulation
Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …