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The population genetics of commensal Escherichia coli
O Tenaillon, D Skurnik, B Picard… - Nature reviews …, 2010 - nature.com
The primary habitat of Escherichia coli is the vertebrate gut, where it is the predominant
aerobic organism, living in symbiosis with its host. Despite the occurrence of recombination …
aerobic organism, living in symbiosis with its host. Despite the occurrence of recombination …
E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity
A Leimbach, J Hacker, U Dobrindt - Between pathogenicity and …, 2013 - Springer
Escherichia coli is a paradigm for a versatile bacterial species which comprises harmless
commensal as well as different pathogenic variants with the ability to either cause intestinal …
commensal as well as different pathogenic variants with the ability to either cause intestinal …
A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome
CN Vassallo, CR Doering, ML Littlehale… - Nature …, 2022 - nature.com
The ancient, ongoing coevolutionary battle between bacteria and their viruses,
bacteriophages, has given rise to sophisticated immune systems including restriction …
bacteriophages, has given rise to sophisticated immune systems including restriction …
Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice
Antibiotic treatments have detrimental effects on the microbiome and lead to antibiotic
resistance. To develop a phage therapy against a diverse range of clinically relevant …
resistance. To develop a phage therapy against a diverse range of clinically relevant …
The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny, and Escherichia core genomic diversity
Z Zhou, NF Alikhan, K Mohamed, Y Fan… - Genome …, 2020 - genome.cshlp.org
EnteroBase is an integrated software environment that supports the identification of global
population structures within several bacterial genera that include pathogens. Here, we …
population structures within several bacterial genera that include pathogens. Here, we …
Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection
E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …
multidrug-resistant bacterial infections and other applications due to their unparalleled …
ClermonTy**: an easy-to-use and accurate in silico method for Escherichia genus strain phyloty**
J Beghain, A Bridier-Nahmias… - Microbial …, 2018 - microbiologyresearch.org
The genus Escherichia is composed of Escherichia albertii, E. fergusonii, five cryptic
Escherichia clades and E. coli sensu stricto. Furthermore, the E. coli species can be divided …
Escherichia clades and E. coli sensu stricto. Furthermore, the E. coli species can be divided …
Bacterial NLR-related proteins protect against phage
EM Kibby, AN Conte, AM Burroughs, TA Nagy… - Cell, 2023 - cell.com
Bacteria use a wide range of immune pathways to counter phage infection. A subset of these
genes shares homology with components of eukaryotic immune systems, suggesting that …
genes shares homology with components of eukaryotic immune systems, suggesting that …
Bacterial persistence promotes the evolution of antibiotic resistance by increasing survival and mutation rates
EM Windels, JE Michiels, M Fauvart… - The ISME …, 2019 - academic.oup.com
Persisters are transiently antibiotic-tolerant cells that complicate the treatment of bacterial
infections. Both theory and experiments have suggested that persisters facilitate genetic …
infections. Both theory and experiments have suggested that persisters facilitate genetic …
The microbiome of uncontacted Amerindians
JC Clemente, EC Pehrsson, MJ Blaser, K Sandhu… - Science …, 2015 - science.org
Most studies of the human microbiome have focused on westernized people with life-style
practices that decrease microbial survival and transmission, or on traditional societies that …
practices that decrease microbial survival and transmission, or on traditional societies that …