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New strategies for the transition-metal catalyzed synthesis of aliphatic amines
A Trowbridge, SM Walton, MJ Gaunt - Chemical reviews, 2020 - ACS Publications
Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …
simple, readily available feedstocks have become a cornerstone of modern synthetic …
Recent updates and future perspectives in aziridine synthesis and reactivity
HJ Dequina, CL Jones, JM Schomaker - Chem, 2023 - cell.com
In this review, selected recent advances in the preparation and reactivity of aziridines using
modern synthetic approaches are highlighted, while comparing these new strategies with …
modern synthetic approaches are highlighted, while comparing these new strategies with …
Aziridine synthesis by coupling amines and alkenes via an electrogenerated dication
Aziridines—three-membered nitrogen-containing cyclic molecules—are important synthetic
targets. Their substantial ring strain and resultant proclivity towards ring-opening reactions …
targets. Their substantial ring strain and resultant proclivity towards ring-opening reactions …
Spatiotemporal microbial evolution on antibiotic landscapes
A key aspect of bacterial survival is the ability to evolve while migrating across spatially
varying environmental challenges. Laboratory experiments, however, often study evolution …
varying environmental challenges. Laboratory experiments, however, often study evolution …
Synthesis and transformations of NH‐sulfoximines
Recent years have seen a marked increase in the occurrence of sulfoximines in the
chemical sciences, often presented as valuable motifs for medicinal chemistry. This has …
chemical sciences, often presented as valuable motifs for medicinal chemistry. This has …
New amination strategies based on nitrogen-centered radical chemistry
T **ong, Q Zhang - Chemical Society Reviews, 2016 - pubs.rsc.org
The interesting and diverse biological activities of nitrogen-containing compounds make the
construction of the C–N bond of great importance. Despite the tremendous advances that …
construction of the C–N bond of great importance. Despite the tremendous advances that …
[HTML][HTML] The use of spirocyclic scaffolds in drug discovery
Y Zheng, CM Tice, SB Singh - Bioorganic & Medicinal Chemistry Letters, 2014 - Elsevier
Owing to their inherent three-dimensionality and structural novelty, spiro scaffolds have
been increasingly utilized in drug discovery. In this brief review, we highlight selected …
been increasingly utilized in drug discovery. In this brief review, we highlight selected …
Computational studies of synthetically relevant homogeneous organometallic catalysis involving Ni, Pd, Ir, and Rh: an overview of commonly employed DFT methods …
T Sperger, IA Sanhueza, I Kalvet… - Chemical …, 2015 - ACS Publications
The field of organometallic catalysis has attracted considerable interest from both academia
and industry due to its broad applications in synthetic transformations. Pd, Ni, Rh, and Ir …
and industry due to its broad applications in synthetic transformations. Pd, Ni, Rh, and Ir …
Atomically dispersed Co-N/C catalyst for divergent synthesis of nitrogen-containing compounds from alkenes
W Xue, Z Zhu, S Chen, B You… - Journal of the American …, 2023 - ACS Publications
Alkene functionalization with a single-atom catalyst (SAC) which merges homogeneous and
heterogeneous catalysis is a fascinating route to obtain high-value-added molecules …
heterogeneous catalysis is a fascinating route to obtain high-value-added molecules …
Design and optimization of catalysts based on mechanistic insights derived from quantum chemical reaction modeling
Until recently, computational tools were mainly used to explain chemical reactions after
experimental results were obtained. With the rapid development of software and hardware …
experimental results were obtained. With the rapid development of software and hardware …