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What are the consequences of the disappearing human microbiota?
Humans and our ancestors have evolved since the most ancient times with a commensal
microbiota. The conservation of indicator species in a niche-specific manner across all of the …
microbiota. The conservation of indicator species in a niche-specific manner across all of the …
Pathogenesis, treatment, and prevention of pneumococcal pneumonia
T van der Poll, SM Opal - The Lancet, 2009 - thelancet.com
Pneumococcus remains the most common cause of community-acquired pneumonia
worldwide. Streptococcus pneumoniae is well adapted to people, and is a frequent …
worldwide. Streptococcus pneumoniae is well adapted to people, and is a frequent …
Pneumococcal vaccination strategies. An update and perspective
Streptococcus pneumoniae is an important global pathogen that causes a wide range of
clinical disease in children and adults. Pneumococcal pneumonia is by far the common …
clinical disease in children and adults. Pneumococcal pneumonia is by far the common …
Interleukin-17A mediates acquired immunity to pneumococcal colonization
Although anticapsular antibodies confer serotype-specific immunity to pneumococci,
children increase their ability to clear colonization before these antibodies appear …
children increase their ability to clear colonization before these antibodies appear …
Pneumococcal capsular polysaccharide structure predicts serotype prevalence
There are 91 known capsular serotypes of Streptococcus pneumoniae. The nasopharyngeal
carriage prevalence of particular serotypes is relatively stable worldwide, but the host and …
carriage prevalence of particular serotypes is relatively stable worldwide, but the host and …
Streptococcus pneumoniae: epidemiology, risk factors, and strategies for prevention
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia,
meningitis, and bacteremia in children and adults. Invasive pneumococcal disease (IPD) …
meningitis, and bacteremia in children and adults. Invasive pneumococcal disease (IPD) …
Mechanisms of Naturally Acquired Immunity to Streptococcus pneumoniae
In this review we give an update on the mechanisms of naturally acquired immunity against
Streptococcus pneumoniae, one of the major human bacterial pathogens that is a common …
Streptococcus pneumoniae, one of the major human bacterial pathogens that is a common …
Niche and neutral effects of acquired immunity permit coexistence of pneumococcal serotypes
Over 90 capsular serotypes of Streptococcus pneumoniae, a common nasopharyngeal
colonizer and major cause of pneumonia, bacteremia, and meningitis, are known. It is …
colonizer and major cause of pneumonia, bacteremia, and meningitis, are known. It is …
A Longitudinal Study of Streptococcus pneumoniae Carriage in a Cohort of Infants and Their Mothers on the Thailand-Myanmar Border
Background Pneumococcal disease is a major cause of childhood death. Almost a third of
the world's children live in Southeast Asia, but there are few data from the region on …
the world's children live in Southeast Asia, but there are few data from the region on …
Interim results of an ecological experiment—conjugate vaccination against the pneumococcus and serotype replacement
Streptococcus pneumoniae has more than 95 serotypes, each of which presumably can
cause sepsis, meningitis, pneumonia, and acute otitis media. Pneumococcal conjugate …
cause sepsis, meningitis, pneumonia, and acute otitis media. Pneumococcal conjugate …