Metal oxide nanomaterials are widely used in practical applications and represent a class of
nanomaterials with the highest global annual production. Many of those, such as TiO2 and …

Comparative genomics shows that a substantial fraction of the genes in sequenced
genomes encodes 'conserved hypothetical'proteins, ie those that are found in organisms …

The proteome refers to the collection of proteins in a given biological organism or system
under a particular set of environmental conditions. The study of proteins, referred to as …

The proteome of growing cells of Bacillus subtilis was analyzed in order to provide the basis
for its application in microbial physiology. DNA arrays were used to calculate the number of …

Database-searching programs generally identify only a fraction of the spectra acquired in a
standard LC/MS/MS study of digested proteins. Subtle variations in database-searching …

Protein identification by tandem mass spectrometry (MS/MS) is key to most proteomics
projects and has been widely explored in bioinformatics research. Obtaining good and …

Tripartite ATP-independent periplasmic (TRAP) transporters are found widely in bacteria
and archaea and consist of three structural domains, a soluble substrate-binding protein (P …

Sialylation of the lipopolysaccharide (LPS) is an important mechanism used by the human
pathogen Haemophilus influenzae to evade the innate immune response of the host. We …

Tandem mass spectrometry has been used increasingly for high-throughput analysis of
complex protein samples. A major challenge lies in the consistent, objective and transparent …

Since our last review in 2002, there have been significant changes in the field of proteomics.
The hype surrounding this field has diminished as it has matured. The initial and overly …