Butyrate producers,“The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics

V Singh, GD Lee, HW Son, H Koh, ES Kim… - Frontiers in …, 2023 - frontiersin.org
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …

Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health

A Mukherjee, C Lordan, RP Ross, PD Cotter - Gut microbes, 2020 - Taylor & Francis
Over the last two decades our understanding of the gut microbiota and its contribution to
health and disease has been transformed. Among a new 'generation'of potentially beneficial …

Small intestine microbiota regulate host digestive and absorptive adaptive responses to dietary lipids

K Martinez-Guryn, N Hubert, K Frazier, S Urlass… - Cell host & …, 2018 - cell.com
The gut microbiota play important roles in lipid metabolism and absorption. However, the
contribution of the small bowel microbiota of mammals to these diet-microbe interactions …

Microbiota composition and metabolism are associated with gut function in Parkinson's disease

MS Cirstea, AC Yu, E Golz, K Sundvick… - Movement …, 2020 - Wiley Online Library
Background Parkinson's disease is characterized by a high burden of gastrointestinal
comorbidities, especially constipation and reduced colonic transit time, and by gut …

[HTML][HTML] Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism

V Leone, SM Gibbons, K Martinez, AL Hutchison… - Cell host & …, 2015 - cell.com
Circadian clocks and metabolism are inextricably intertwined, where central and hepatic
circadian clocks coordinate metabolic events in response to light-dark and sleep-wake …

Gut butyrate-producers confer post-infarction cardiac protection

HC Chen, YW Liu, KC Chang, YW Wu, YM Chen… - Nature …, 2023 - nature.com
The gut microbiome and its metabolites are increasingly implicated in several
cardiovascular diseases, but their role in human myocardial infarction (MI) injury responses …

Revealing the bacterial butyrate synthesis pathways by analyzing (meta) genomic data

M Vital, AC Howe, JM Tiedje - MBio, 2014 - Am Soc Microbiol
Butyrate-producing bacteria have recently gained attention, since they are important for a
healthy colon and when altered contribute to emerging diseases, such as ulcerative colitis …

Systemic availability and metabolism of colonic‐derived short‐chain fatty acids in healthy subjects: a stable isotope study

E Boets, SV Gomand, L Deroover… - The Journal of …, 2017 - Wiley Online Library
Key points The short‐chain fatty acids (SCFAs) are bacterial metabolites produced during
the colonic fermentation of undigested carbohydrates, such as dietary fibre and prebiotics …

Colon microbiota fermentation of dietary prebiotics towards short-chain fatty acids and their roles as anti-inflammatory and antitumour agents: A review

J Fernández, S Redondo-Blanco… - Journal of Functional …, 2016 - Elsevier
Some plant polysaccharides cannot be digested by humans, arriving intact to the colon,
where they are fermented by a distinct group of anaerobic beneficial bacterial species …

FunGene: the functional gene pipeline and repository

JA Fish, B Chai, Q Wang, Y Sun, CT Brown… - Frontiers in …, 2013 - frontiersin.org
Ribosomal RNA genes have become the standard molecular markers for microbial
community analysis for good reasons, including universal occurrence in cellular organisms …