Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

L Gourdon, K Cariou, G Gasser - Chemical Society Reviews, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) are therapeutic
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …

Reversal of cisplatin chemotherapy resistance by glutathione-resistant copper-based nanomedicine via cuproptosis

Y Lu, Q Pan, W Gao, Y Pu, B He - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Platinum-based chemotherapy is widely used to treat various cancers. However, exogenous
platinum is likely to cause severe side effects and drug resistance induced by upregulated …

Platinum-containing heterometallic complexes in cancer therapy: advances and perspectives

L Ma, L Li, G Zhu - Inorganic Chemistry Frontiers, 2022 - pubs.rsc.org
Platinum-based anticancer drugs are among the most widely used antineoplastics in clinical
settings. Their therapeutic applications and outcomes are, however, greatly hampered by …

Diverse coordination of isoniazid hydrazone Schiff base ligand towards iron (III): Synthesis, characterization, SC-XRD, HSA, QTAIM, MEP, NCI, NBO and DFT study

H Kargar, M Fallah-Mehrjardi… - Journal of Molecular …, 2022 - Elsevier
A new iron (III) complex has been successfully prepared by the reaction of an ONO donor
Schiff base, derived by condensing isoniazid and 3-ethoxysalicylaldehyde, with Fe (acac) 3 …

Recent development of copper (II) complexes of polypyridyl ligands in chemotherapy and photodynamic therapy

J Rani J, S Roy - ChemMedChem, 2023 - Wiley Online Library
Cancer is a deadly disease associated with abnormal cell growth and invasion to various
parts of the body. Many drugs such as cisplatin and carboplatin have been used for the …

The role of complexes of biogenic metals in living organisms

I Kostova - Inorganics, 2023 - mdpi.com
Biogenic metals and their various inorganic, organometallic, and coordination compounds
are comprehensively studied and extensively used in medical practice. Since the biogenic …

Current roles of metals in arming sonodynamic cancer therapy

Z Chen, X Wu, J Liang, H Chao - Coordination Chemistry Reviews, 2024 - Elsevier
Emerging sonodynamic therapy strategies shed light on conquering oxygen dependence
and penetration restriction in photodynamic therapy for non-invasive tumor treatments …

Promising heterometallic compounds as anticancer agents: Recent studies in vivo

JE López-Hernández, M Contel - Current opinion in chemical biology, 2023 - Elsevier
Over the past decade, interest on multitarget anticancer drugs-including heterometallic
compounds-has increased considerably. Heterometallic species display improved efficacy …

Recent advances in iron-complexes as drug candidates for cancer therapy: Reactivity, mechanism of action and metabolites

M Bouché, C Hognon, S Grandemange, A Monari… - Dalton …, 2020 - pubs.rsc.org
In this perspective, we discuss iron-complexes as drug candidates that are promising
alternatives to conventional platinum-based chemotherapies owing to their broad range of …