Background Cancer is the most prevalent cause of death globally, and radiotherapy is
considered the standard of care for most solid tumors, including lung, breast, esophageal …

Approximately 50% of all patients with cancer receive radiation therapy at some point during
the course of their treatment, and the majority of these patients are treated with curative …

It is generally believed that diseases caused by oxidative stress should be treated with
antioxidants. However, clinical trials with such antioxidants as ascorbic acid and vitamin E …

Since observations from the beginning of the last century, it has become well established
that solid tumors may contain oxygen-deficient hypoxic areas and that cells in such areas …

Breast cancer (BC) is the most common malignancy and the second cause of cancer-
specific death in women from high-income countries. Recently, gut microbiota dysbiosis …

Hypoxia is a critical hallmark of solid tumors and involves enhanced cell survival,
angiogenesis, glycolytic metabolism, and metastasis. Hyperbaric oxygen (HBO) treatment …

A large body of clinical evidence exists to suggest that tumor hypoxia negatively impacts
radiotherapy. As a result, there has been longstanding active research into novel methods of …

Oxygen treatment has been a cornerstone of acute medical care for numerous pathological
states. Initially, this was supported by the assumed need to avoid hypoxaemia and tissue …

Glioblastoma (GBM) tumors are the most aggressive primary brain tumors in adults that,
despite maximum treatment, carry a dismal prognosis. GBM tumors exhibit tissue hypoxia …

Abstract Hyperbaric oxygen (HBO) therapy is widely used as an adjunctive treatment for
various pathological states, predominantly related to hypoxic and/or ischaemic conditions. It …