[HTML][HTML] Predictors of chemotherapy efficacy in non-small-cell lung cancer: a challenging landscape
Background Conventional cytotoxic chemotherapy (CCC) is the backbone of non-small-cell
lung cancer (NSCLC) treatment since decades and still represents a key element of the …
lung cancer (NSCLC) treatment since decades and still represents a key element of the …
Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects normal
functions of the brain. Currently, AD is one of the leading causes of death in developed …
functions of the brain. Currently, AD is one of the leading causes of death in developed …
[HTML][HTML] MARK2 regulates directed cell migration through modulation of myosin II contractility and focal adhesion organization
Cancer cell migration during metastasis is mediated by a highly polarized cytoskeleton.
MARK2 and its invertebrate homolog Par1B are kinases that regulate the microtubule …
MARK2 and its invertebrate homolog Par1B are kinases that regulate the microtubule …
[HTML][HTML] MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway
MARKs kinase belongs to an AMPK-related family kinase plays a critical role in tumor
progression, but its exact role and contribution of four different isoforms remain largely …
progression, but its exact role and contribution of four different isoforms remain largely …
Long non-coding RNA ABHD11-AS1 facilitates the progression of cervical cancer by competitively binding to miR-330–5p and upregulating MARK2
S Hou, X Zhang, J Yang - Experimental Cell Research, 2022 - Elsevier
Cervical cancer (CC) is among the most prevalent gynecological malignancies. Participation
of long non-coding RNA (lncRNA) in modulating biological behaviors of CC cells has been …
of long non-coding RNA (lncRNA) in modulating biological behaviors of CC cells has been …
Role of MARK2 in the nervous system and cancer
Y Lei, R Zhang, F Cai - Cancer Gene Therapy, 2024 - nature.com
Abstract Microtubule-Affinity Regulating Kinase 2 (MARK2), a member of the
serine/threonine protein kinase family, phosphorylates microtubule-associated proteins …
serine/threonine protein kinase family, phosphorylates microtubule-associated proteins …
Advancements in mTOR Inhibitors for Non-Small-Cell Lung Cancer: Mechanisms, Efficacy, and Future Perspectives
This account comprehensively reviews the recent advancements in the development of
mechanistic target of rapamycin (mTOR) inhibitors targeting non-small-cell lung cancer …
mechanistic target of rapamycin (mTOR) inhibitors targeting non-small-cell lung cancer …
Expression of MARK2 in hepatocellular carcinoma and its effect on the migration of hepatocellular carcinoma cells
LI Huiqin, WU **nai, D Wenjie - China Oncology, 2018 - china-oncology.com
Background and purpose: Hepatocellular carcinoma (HCC) is one of the common
malignancies in China. The mechanism of its occurrence is not yet clear. The aim of this …
malignancies in China. The mechanism of its occurrence is not yet clear. The aim of this …
Intermolecular and Intramolecular Interactions Controlling the Localization and Activity of the Yeast Kinases Kin1 and Kin2
KA Weise - 2021 - search.proquest.com
Abstract Kin1 and Kin2 (Kin1/2), the S. cerevisiae orthologs of the mammalian microtubule
affinity-regulating kinases (MARKs), regulate a variety of important cellular functions …
affinity-regulating kinases (MARKs), regulate a variety of important cellular functions …
MARK2 在肝癌中的表达及其对肝癌细胞迁移的影响
**会琴， 吴欣爱， 董文杰 - **癌症杂志, 2018 - china-oncology.com
背景与目的: 肝细胞癌是我国常见恶性肿瘤之一, 其发生机制目前尚未明确.
该研究旨在探讨微管亲和性调节激酶2 (microtubule affinity-regulating kinase 2, MARK2) …
该研究旨在探讨微管亲和性调节激酶2 (microtubule affinity-regulating kinase 2, MARK2) …