Plasmodium vivax: the potential obstacles it presents to malaria elimination and eradication

K Habtamu, B Petros, G Yan - Tropical Diseases, Travel Medicine and …, 2022 - Springer
Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …

Plasmodium genomics: an approach for learning about and ending human malaria

JA Garrido-Cardenas, L González-Cerón… - Parasitology …, 2019 - Springer
Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …

Distinctive genetic structure and selection patterns in Plasmodium vivax from South Asia and East Africa

ED Benavente, E Manko, J Phelan, M Campos… - Nature …, 2021 - nature.com
Despite the high burden of Plasmodium vivax malaria in South Asian countries, the genetic
diversity of circulating parasite populations is not well described. Determinants of …

Genome sequencing of Plasmodium malariae identifies continental segregation and mutations associated with reduced pyrimethamine susceptibility

A Ibrahim, F Mohring, E Manko… - Nature …, 2024 - nature.com
Plasmodium malariae parasites are widely observed across the tropics and sub-tropics. This
slow-growing species, known to maintain chronic asymptomatic infections, has been …

Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

S Auburn, ED Benavente, O Miotto, RD Pearson… - Nature …, 2018 - nature.com
The incidence of Plasmodium vivax infection has declined markedly in Malaysia over the
past decade despite evidence of high-grade chloroquine resistance. Here we investigate the …

Molecular approaches to determine the multiplicity of Plasmodium infections

D Zhong, C Koepfli, L Cui, G Yan - Malaria journal, 2018 - Springer
Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Using deep learning to identify recent positive selection in malaria parasite sequence data

W Deelder, ED Benavente, J Phelan, E Manko… - Malaria journal, 2021 - Springer
Abstract Background Malaria, caused by Plasmodium parasites, is a major global public
health problem. To assist an understanding of malaria pathogenesis, including drug …

[KNJIGA][B] Parasitology: a conceptual approach

ES Loker, BV Hofkin - 2022 - taylorfrancis.com
Produced amidst the still rippling effects of a pandemic and as the world experiences the
increasing burden of global warming and a rapidly changing biosphere, the second edition …

Plasmodium vivax populations in the western Greater Mekong Subregion evaluated using a genetic barcode

Y Hu, Y Li, AM Brashear, W Zeng, Z Wu… - PLOS Neglected …, 2024 - journals.plos.org
An improved understanding of the Plasmodium vivax populations in the Great Mekong
Subregion (GMS) is needed to monitor the progress of malaria elimination. This study aimed …

Genomic analysis of global Plasmodium vivax populations reveals insights into the evolution of drug resistance

GC Ngwana-Joseph, JE Phelan, E Manko… - Nature …, 2024 - nature.com
Increasing reports of chloroquine resistance (CQR) in Plasmodium vivax endemic regions
have led to several countries, including Indonesia, to adopt dihydroarteminsin-piperaquine …