Studies of mammalian development have advanced our understanding of the genetic,
epigenetic, and cellular processes that orchestrate embryogenesis and have uncovered …

The ability to study human post-implantation development remains limited owing to ethical
and technical challenges associated with intrauterine development after implantation …

An organoid is a 3D organization of cells that can recapitulate some of the structure and
function of native tissue. Recent work has seen organoids gain prominence as a valuable …

Stem cell-based embryo models offer unprecedented experimental tools for studying early
human development. The usefulness of embryo models hinges on their molecular, cellular …

In vitro stem cell models that replicate human gastrulation have been generated, but they
lack the essential extraembryonic cells needed for embryonic development, morphogenesis …

Recently, several studies using cultures of human embryos together with single-cell RNA-
seq analyses have revealed differences between humans and mice, necessitating the study …

Implantation of the human embryo begins a critical developmental stage that comprises
profound events including axis formation, gastrulation and the emergence of haematopoietic …

With the advancement of human stem cell cultures and interest in understanding human
embryogenesis, human blastocyst-like structures, or human blastoids, are being developed …

Recent discoveries in stem cell and developmental biology have introduced a new era
marked by the generation of in vitro models that recapitulate early mammalian development …

Neurodevelopment involves the migration, projection, and integration of various cell types
across different regions of the nervous system. Assembloids are self-organizing systems …