Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic
producers are an integral part of the growing antibiotic resistance threat. The origins of …

Background Antibiotic resistance developed by bacteria is a significant threat to global
health. Antibiotic resistance genes (ARGs) spread across different bacterial populations …

Aminoglycosides are a group of antibiotics used since the 1940s to primarily treat a broad
spectrum of bacterial infections. The primary resistance mechanism against these antibiotics …

The utility of endophytic bacteria in Cadmium (Cd) remediation has gained significant
attention due to their ability to alleviate metal-induced stress and enhance plant growth …

Herbicides are one of the most widely used chemicals in agriculture. While they are known
to be harmful to nontarget organisms, the effects of herbicides on the composition and …

Tetracyclines have been foundational antibacterial agents for more than 70 years. Renewed
interest in tetracycline antibiotics is being driven by advancements in tetracycline synthesis …

General control non-repressible 5 (GCN5)-related N-acetyltransferases (GNAT) catalyze the
transfer of an acyl moiety from acyl coenzyme A (acyl-CoA) to a diverse group of substrates …

The AMP-forming acetyl-CoA synthetase is regulated by lysine acetylation both in bacteria
and eukaryotes. However, the underlying mechanism is poorly understood. The Bacillus …

Lipopeptides represent a large group of microbial natural products that include important
antibacterial and antifungal drugs and some of the most-powerful known biosurfactants. The …