Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …

The protective blood–brain barrier has a major role in ensuring normal brain function by
severely limiting and tightly controlling the ingress of substances into the brain from the …

Radiotherapy, a mainstay of first‐line cancer treatment, suffers from its high‐dose radiation‐
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …

Photoluminescence (PL) imaging has become a fundamental tool in disease diagnosis,
therapeutic evaluation, and surgical navigation applications. However, it remains a big …

Given the difficulties of biodegradation of mesoporous silica nanoparticles (NPs),
enrichment and penetration of tumor sites, and real-time monitoring of the treatment process …

Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …

Celastrol (CEL), an active compound isolated from the root of Tripterygium wilfordii, exhibits
broad anticancer activities. However, its poor stability, narrow therapeutic window and …

CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …

Background and purpose Brain metastasis impacts greatly on patients' quality of life and
survival. The phase I NANO-RAD trial assessed the safety and maximum tolerated dose of …