Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

The human insulin-like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2/IMP2) is
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …

RNA binding proteins that act at the post-transcriptional level display a richness of
mechanisms to modulate the transcriptional output and respond to changing cellular …

Background Genetic alterations of somatic cells can drive non-malignant clone formation
and promote cancer initiation. However, the link between these processes remains unclear …

RNA can be modified by over 170 types of distinct chemical modifications, and the most
abundant internal modification of mRNA in eukaryotes is N6-methyladenosine (m 6 A). The …

Epitranscriptomic modification of RNA regulates human development, health, and disease.
The true diversity of the transcriptome in breast cancer including chemical modification of …

Abstract N6-methyladenosine (m6A) modification, as one of the most common types of inner
RNA modification in eukaryotes, plays a multifunctional role in normal and abnormal …

Background Clear cell renal cell carcinoma (ccRCC) is a common malignant tumour of the
urinary tract. The major causes of poor prognosis are the lack of early diagnosis and …

N6-methyladenosine (m6A) RNA methylation is identified as the most common, abundant
and reversible RNA epigenetic modification in messenger RNA (mRNA) and non-coding …

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) serve essential biological
functions as post-transcriptional performers, participating in the acquisition or maintenance …