Environmental and industrial lead exposures continue to pose major public health problems
in children and in adults. Acute exposure to high concentrations of lead can result in …

An elevated uric acid level is associated with cardiovascular disease. Hyperuricemia is
predictive for the development of both hypertension and coronary artery disease; it is …

Metals differ from other toxic substances in that they are neither created nor destroyed by
humans. Nevertheless, their utilization by humans influences the potential for health effects …

Background Declines in blood lead levels between 1976 and 1991 among US adults have
been previously reported. More recent trends in blood lead levels and the association of …

Uric acid metabolism is reviewed as it relates mainly to kidney and electrolyte disorders, with
emphasis on the difficulties in understanding urate transport because of its bidirectional …

Blood lead and chronic kidney disease in the general United States population: Results from
NHANES III. Background High lead exposure is associated with hypertension and renal …

Lead toxicity causes hematological, gastrointestinal, and neurological dysfunction in adults
and children. Symptoms are usually noted with blood lead greater than 1.93 μmol/L. Severe …

Exposure to lead results in accumulation in proximal renal tubular lining cells in the form of
morphologically discernible inclusion bodies which are lead-protein complexes. Acute …

Purpose. Common sources of lead exposure, the primary clinical effects of lead toxicity, and
current recommendations for managing lead toxicity, including chelation therapy, are …

Metals, particularly heavy metals such as lead, mercury, cadmium, and arsenic, constitute
significant potential threats to human health in both occupational and environmental …