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Cerebral small vessel disease pathology in COVID-19 patients: A systematic review
Cerebral small vessel disease (CSVD) is the leading cause of vascular cognitive impairment
and is associated with COVID-19. However, contributing factors that often accompany CSVD …
and is associated with COVID-19. However, contributing factors that often accompany CSVD …
Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy
Some humans age faster than others. Variation in biological aging can be measured in
midlife, but the implications of this variation are poorly understood. We tested associations …
midlife, but the implications of this variation are poorly understood. We tested associations …
MRI-based biomarkers of accelerated aging and dementia risk in midlife: how close are we?
The global population is aging, leading to an increasing burden of age-related
neurodegenerative disease. Efforts to intervene against age-related dementias in older …
neurodegenerative disease. Efforts to intervene against age-related dementias in older …
Axenfeld-Rieger syndrome: more than meets the eye
Background Axenfeld-Rieger syndrome (ARS) is characterised by typical anterior segment
anomalies, with or without systemic features. The discovery of causative genes identified …
anomalies, with or without systemic features. The discovery of causative genes identified …
White matter hyperintensities across the adult lifespan: relation to age, Aβ load, and cognition
Background White matter hyperintensities (WMH) are very frequent in older adults and
associated with worse cognitive performance. Little is known about the links between WMH …
associated with worse cognitive performance. Little is known about the links between WMH …
Age-, sex-, and pathology-related variability in brain structure and cognition
This work aimed to investigate potential pathways linking age and imaging measures to
early age-and pathology-related changes in cognition. We used [18F]-Flutemetamol …
early age-and pathology-related changes in cognition. We used [18F]-Flutemetamol …
White matter hyperintensities segmentation using an ensemble of neural networks
White matter hyperintensities (WMHs) represent the most common neuroimaging marker of
cerebral small vessel disease (CSVD). The volume and location of WMHs are important …
cerebral small vessel disease (CSVD). The volume and location of WMHs are important …
Associations between brain volumes and cognitive tests with hypertensive burden in UK Biobank
Background: Mid-life hypertension is an established risk factor for cognitive impairment and
dementia and related to greater brain atrophy and poorer cognitive performance. Previous …
dementia and related to greater brain atrophy and poorer cognitive performance. Previous …
Benchmarking the influence of pre-training on explanation performance in MR image classification
Convolutional Neural Networks (CNNs) are frequently and successfully used in medical
prediction tasks. They are often used in combination with transfer learning, leading to …
prediction tasks. They are often used in combination with transfer learning, leading to …
Central arterial stiffness, brain white matter hyperintensity and total brain volume across the adult lifespan
Objectives: Mounting evidence suggests that central arterial stiffening is associated with
brain ageing in older adults. The purpose of this study was to determine the associations of …
brain ageing in older adults. The purpose of this study was to determine the associations of …