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Azalides from azithromycin to new azalide derivatives
S Mutak - The Journal of Antibiotics, 2007 - nature.com
Azalides are semi-synthetic macrolides, in which a nitrogen atom is introduced into a
macrolactone ring via a Beckmann rearrangement. Starting from erythromycin, oximes …
macrolactone ring via a Beckmann rearrangement. Starting from erythromycin, oximes …
Macrolide hybrid compounds: drug discovery opportunities in anti-infective and anti-inflammatory area
H Cipcic Paljetak, L Tomaskovic… - Current topics in …, 2017 - ingentaconnect.com
Macrolides, polyketide natural products, and their 15-membered semi-synthetic derivatives
are composed of substituted macrocyclic lactone ring and used primarily as potent …
are composed of substituted macrocyclic lactone ring and used primarily as potent …
Bifunctional heterocyclic compounds and methods of making and using same
D Wang, JA Sutcliffe, AK Oyelere, TS Mcconnell… - US Patent …, 2008 - Google Patents
2014-09-24 Assigned to RIB-X PHARMACEUTICALS, INC. reassignment RIB-X
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Method of identifying improved conjugates of biologically active compounds
This invention features a method of identifying a compound useful for enhancing efficacy of
a therapeutic agent. The method includes incubating a compound in blood cells; sepa rating …
a therapeutic agent. The method includes incubating a compound in blood cells; sepa rating …
Non-peptide macrocyclic histone deacetylese (HDAC) inhibitors and methods of making and using thereof
A Oyelere, S Tapadar - US Patent 8,871,728, 2014 - Google Patents
D is an alkyl or aryl group, A is a linking group connected to D, B is an alkyl, alkylaryl or
alkylheteroaryl spacer group, ZBG is a Zinc Binding Group, RR and Ra are independently …
alkylheteroaryl spacer group, ZBG is a Zinc Binding Group, RR and Ra are independently …
Bifunctional heterocyclic compounds and methods of making and using same
D Wang, JA Sutcliffe, AK Oyelere, TS Mcconnell… - US Patent …, 2006 - Google Patents
2004-10-12 Assigned to RIB-X PHARMACEUTICALS, INC. reassignment RIB-X
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Macrocyclic compounds and methods of making and using the same
JJ Farmer, A Bhattacharjee, Y Chen… - US Patent …, 2012 - Google Patents
2007-06-26 Assigned to RIB-X PHARMACEUTICALS, INC. reassignment RIB-X
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Delayed-release formulation for reducing the frequency of urination and method of use thereof
US Patent App. 14/175,183, 2014 - Google Patents
Methods and compositions for reducing the frequency of urination are disclosed. One
method comprises administering to a subject in need thereof an effective amount of a …
method comprises administering to a subject in need thereof an effective amount of a …
Compounds with anti-inflammatory activity
M Mercep, M Mesic, L Tomaskovic - US Patent 7,579,334, 2009 - Google Patents
US7579334B2 - Compounds with anti-inflammatory activity - Google Patents US7579334B2 -
Compounds with anti-inflammatory activity - Google Patents Compounds with anti-inflammatory …
Compounds with anti-inflammatory activity - Google Patents Compounds with anti-inflammatory …
Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
BACKGROUND 0002. Successful therapy with a pharmaceutical agent requires that the
agent satisfy numerous requirements imposed by the physiology of the host and of the …
agent satisfy numerous requirements imposed by the physiology of the host and of the …