[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
Subcritical water for the extraction and hydrolysis of protein and other fractions in biorefineries from agro-food wastes and algae: A review
M Álvarez-Viñas, P Rodríguez-Seoane… - Food and Bioprocess …, 2021 - Springer
Low-cost plant and algal biomass are increasingly demanded as a source of proteins, and
also, peptides and amino acids are gaining interest for their biological and functional …
also, peptides and amino acids are gaining interest for their biological and functional …
β-Casomorphin: A complete health perspective
M Thiruvengadam, B Venkidasamy, P Thirupathi… - Food Chemistry, 2021 - Elsevier
Abstract β-Casomorphin-7 (BCM-7) is a heptapeptide dietary molecule derived from the
digestion of the β-casein of dairy and dairy products. In this review, we have covered the …
digestion of the β-casein of dairy and dairy products. In this review, we have covered the …
[HTML][HTML] Thrombosis and COVID-19: The Potential role of nutrition
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the
coronavirus disease (COVID-19), is a contagion that has rapidly spread around the globe …
coronavirus disease (COVID-19), is a contagion that has rapidly spread around the globe …
The Synergistic Effect of Ginkgo biloba Extract 50 and Aspirin Against Platelet Aggregation
J Ke, MT Li, YJ Huo, YQ Cheng, SF Guo… - Drug Design …, 2021 - Taylor & Francis
Purpose We aimed to investigate potential synergistic antiplatelet effects of Ginkgo biloba
extract (GBE50) in combination with aspirin using in vitro models. Methods Arachidonic acid …
extract (GBE50) in combination with aspirin using in vitro models. Methods Arachidonic acid …
[PDF][PDF] Oral delivery of peptide and protein therapeutics: challenges and strategies.
This review explores the challenges and strategies in oral delivery of peptide and protein
therapeutics. Physiological barriers such as the gastrointestinal tract, enzymatic …
therapeutics. Physiological barriers such as the gastrointestinal tract, enzymatic …
A TNF-α blocking peptide that reduces NF-κB and MAPK activity for attenuating inflammation
Y Wang, R Ye, L Fan, X Zhao, L Li, H Zheng… - Bioorganic & Medicinal …, 2023 - Elsevier
Overexpression of tumor necrosis factor-α (TNF-α) is implicated in many inflammatory
diseases, including septic shock, hepatitis, asthma, insulin resistance and autoimmune …
diseases, including septic shock, hepatitis, asthma, insulin resistance and autoimmune …
The Current and Promising Oral Delivery Methods for Protein-and Peptide-Based Drugs
M Nicze, M Borówka, A Dec, A Niemiec… - International Journal of …, 2024 - mdpi.com
Drugs based on peptides and proteins (PPs) have been widely used in medicine, beginning
with insulin therapy in patients with diabetes mellitus over a century ago. Although the oral …
with insulin therapy in patients with diabetes mellitus over a century ago. Although the oral …
Hydroxyls on the B ring and gallic acyl are essential for catechins to restrain ADP-induced thrombosis
Y Pan, X Feng, S Zhou, S Yang, P Qiu, S Gong… - Food & Function, 2023 - pubs.rsc.org
Platelet hyperactivation could lead to various cardiovascular and cerebrovascular diseases,
while epidemiological analyses have found that long-term tea drinking could prevent and …
while epidemiological analyses have found that long-term tea drinking could prevent and …
Unveiling the Potent Fibrino(geno)lytic, Anticoagulant, and Antithrombotic Effects of Papain, a Cysteine Protease from Carica papaya Latex Using κ-Carrageenan Rat …
HR Yang, MN Zahan, Y Yoon, K Kim… - International Journal of …, 2023 - mdpi.com
While fibrinolytic enzymes and thrombolytic agents offer assistance in treating
cardiovascular diseases, the existing options are associated with a range of adverse effects …
cardiovascular diseases, the existing options are associated with a range of adverse effects …