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Active nematics
A Doostmohammadi, J Ignés-Mullol… - Nature …, 2018 - nature.com
Active matter extracts energy from its surroundings at the single particle level and transforms
it into mechanical work. Examples include cytoskeleton biopolymers and bacterial …
it into mechanical work. Examples include cytoskeleton biopolymers and bacterial …
Materials learning from life: concepts for active, adaptive and autonomous molecular systems
R Merindol, A Walther - Chemical Society Reviews, 2017 - pubs.rsc.org
Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …
MINFLUX dissects the unimpeded walking of kinesin-1
JO Wirth, L Scheiderer, T Engelhardt, J Engelhardt… - Science, 2023 - science.org
We introduce an interferometric MINFLUX microscope that records protein movements with
up to 1.7 nanometer per millisecond spatiotemporal precision. Such precision has …
up to 1.7 nanometer per millisecond spatiotemporal precision. Such precision has …
Direct observation of motor protein step** in living cells using MINFLUX
T Deguchi, MK Iwanski, EM Schentarra, C Heidebrecht… - Science, 2023 - science.org
Dynamic measurements of molecular machines can provide invaluable insights into their
mechanism, but these measurements have been challenging in living cells. Here, we …
mechanism, but these measurements have been challenging in living cells. Here, we …
Ultra-extensible ribbon-like magnetic microswarm
Various types of structures self-organised by animals exist in nature, such as bird flocks and
insect swarms, which stem from the local communications of vast numbers of limited …
insect swarms, which stem from the local communications of vast numbers of limited …
Spatially stable mitochondrial compartments fuel local translation during plasticity
V Rangaraju, M Lauterbach, EM Schuman - Cell, 2019 - cell.com
Local translation meets protein turnover and plasticity demands at synapses, however, the
location of its energy supply is unknown. We found that local translation in neurons is …
location of its energy supply is unknown. We found that local translation in neurons is …
Spontaneous motion in hierarchically assembled active matter
With remarkable precision and reproducibility, cells orchestrate the cooperative action of
thousands of nanometre-sized molecular motors to carry out mechanical tasks at much …
thousands of nanometre-sized molecular motors to carry out mechanical tasks at much …
Motor proteins
HL Sweeney, ELF Holzbaur - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …
Energy metabolism in ALS: an underappreciated opportunity?
T Vandoorne, K De Bock, L Van Den Bosch - Acta neuropathologica, 2018 - Springer
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …
Bidirectional cargo transport: moving beyond tug of war
WO Hancock - Nature reviews Molecular cell biology, 2014 - nature.com
Vesicles, organelles and other intracellular cargo are transported by kinesin and dynein
motors, which move in opposite directions along microtubules. This bidirectional cargo …
motors, which move in opposite directions along microtubules. This bidirectional cargo …