A comprehensive review on the biological interest of quinoline and its derivatives

BS Matada, R Pattanashettar, NG Yernale - Bioorganic & Medicinal …, 2021 - Elsevier
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine

VBR da Silva, BRKL Campos, JF de Oliveira… - Bioorganic & medicinal …, 2017 - Elsevier
Neglected tropical diseases (NTDs) are a group of diseases that, besides prevailing in
poverty conditions, contribute to the maintenance of social inequality, being a strong barrier …

A General and Highly Selective Cobalt‐Catalyzed Hydrogenation of N‐Heteroarenes under Mild Reaction Conditions

R Adam, JR Cabrero‐Antonino… - Angewandte …, 2017 - Wiley Online Library
Herein, a general and efficient method for the homogeneous cobalt‐catalyzed
hydrogenation of N‐heterocycles, under mild reaction conditions, is reported. Key to success …

A General Catalyst Based on Cobalt Core–Shell Nanoparticles for the Hydrogenation of N‐Heteroarenes Including Pyridines

K Murugesan, VG Chandrashekhar… - Angewandte Chemie …, 2020 - Wiley Online Library
Herein, we report the synthesis of specific silica‐supported Co/Co3O4 core–shell based
nanoparticles prepared by template synthesis of cobalt‐pyromellitic acid on silica and …

Mefloquine—an aminoalcohol with promising antischistosomal properties in mice

J Keiser, J Chollet, SH **ao, JY Mei… - PLoS neglected …, 2009 - journals.plos.org
Background The treatment and control of schistosomiasis, an often neglected tropical
disease that exacerbates poverty, depends on a single drug, praziquantel. The large-scale …

Transfer hydrogenation of pyridinium and quinolinium species using ethanol as a hydrogen source to access saturated N-heterocycles

N KumaráMaurya, M RaoáKuram - Chemical Communications, 2022 - pubs.rsc.org
Catalytic transfer hydrogenation (TH) for the reduction of heterocycles is an emerging
strategy for accessing biologically active saturated N-heterocycles. Herein, we report a TH …

Transfer hydrogenation of N-heteroarenes with 2-propanol and ethanol enabled by manganese catalysis

Y Gong, J He, X Wen, H **, Z Wei, W Liu - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
A convenient manganese catalyzed transfer hydrogenation of N-heteroarenes by using
alcohols as hydrogen sources is presented. Ideal results are achieved by applying the 6 …

Iridium Complex-Catalyzed Transfer Hydrogenation of N-Heteroarenes and Tentative Asymmetric Synthesis

L Ouyang, Y **a, J Liao, R Miao, X Yang, R Luo - ACS omega, 2021 - ACS Publications
An iridium-catalyzed transfer hydrogenation of N-heteroarenes to access a series of
substituted 1, 2, 3, 4-tetrahydroquinoline derivatives in excellent yields is disclosed. This …

Ir-catalyzed selective reductive N-formylation and transfer hydrogenation of N-heteroarenes

R Luo, S Wang, Y Liang, J Tong, J Liao… - Organometallics, 2024 - ACS Publications
Selective functionalization has numerous potential applications in the modification of
bioactive compounds and pharmaceuticals. Herein, we advance a new approach for the …

Cobalt-catalysed transfer hydrogenation of quinolines and related heterocycles using formic acid under mild conditions

JR Cabrero-Antonino, R Adam, K Junge… - Catalysis Science & …, 2017 - pubs.rsc.org
Herein, we report the first example of homogeneous non-noble metal-catalyzed transfer
hydrogenation of N-heteroarenes. The combination of Co (BF4) 2· 6H2O with tris (2 …