A comprehensive review on the biological interest of quinoline and its derivatives
BS Matada, R Pattanashettar, NG Yernale - Bioorganic & Medicinal …, 2021 - Elsevier
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …
significant assembly motif for the development of new drug entities. Quinoline and its …
Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine
VBR da Silva, BRKL Campos, JF de Oliveira… - Bioorganic & medicinal …, 2017 - Elsevier
Neglected tropical diseases (NTDs) are a group of diseases that, besides prevailing in
poverty conditions, contribute to the maintenance of social inequality, being a strong barrier …
poverty conditions, contribute to the maintenance of social inequality, being a strong barrier …
A General and Highly Selective Cobalt‐Catalyzed Hydrogenation of N‐Heteroarenes under Mild Reaction Conditions
Herein, a general and efficient method for the homogeneous cobalt‐catalyzed
hydrogenation of N‐heterocycles, under mild reaction conditions, is reported. Key to success …
hydrogenation of N‐heterocycles, under mild reaction conditions, is reported. Key to success …
A General Catalyst Based on Cobalt Core–Shell Nanoparticles for the Hydrogenation of N‐Heteroarenes Including Pyridines
Herein, we report the synthesis of specific silica‐supported Co/Co3O4 core–shell based
nanoparticles prepared by template synthesis of cobalt‐pyromellitic acid on silica and …
nanoparticles prepared by template synthesis of cobalt‐pyromellitic acid on silica and …
Mefloquine—an aminoalcohol with promising antischistosomal properties in mice
J Keiser, J Chollet, SH **ao, JY Mei… - PLoS neglected …, 2009 - journals.plos.org
Background The treatment and control of schistosomiasis, an often neglected tropical
disease that exacerbates poverty, depends on a single drug, praziquantel. The large-scale …
disease that exacerbates poverty, depends on a single drug, praziquantel. The large-scale …
Transfer hydrogenation of pyridinium and quinolinium species using ethanol as a hydrogen source to access saturated N-heterocycles
N KumaráMaurya, M RaoáKuram - Chemical Communications, 2022 - pubs.rsc.org
Catalytic transfer hydrogenation (TH) for the reduction of heterocycles is an emerging
strategy for accessing biologically active saturated N-heterocycles. Herein, we report a TH …
strategy for accessing biologically active saturated N-heterocycles. Herein, we report a TH …
Transfer hydrogenation of N-heteroarenes with 2-propanol and ethanol enabled by manganese catalysis
A convenient manganese catalyzed transfer hydrogenation of N-heteroarenes by using
alcohols as hydrogen sources is presented. Ideal results are achieved by applying the 6 …
alcohols as hydrogen sources is presented. Ideal results are achieved by applying the 6 …
Iridium Complex-Catalyzed Transfer Hydrogenation of N-Heteroarenes and Tentative Asymmetric Synthesis
L Ouyang, Y **a, J Liao, R Miao, X Yang, R Luo - ACS omega, 2021 - ACS Publications
An iridium-catalyzed transfer hydrogenation of N-heteroarenes to access a series of
substituted 1, 2, 3, 4-tetrahydroquinoline derivatives in excellent yields is disclosed. This …
substituted 1, 2, 3, 4-tetrahydroquinoline derivatives in excellent yields is disclosed. This …
Ir-catalyzed selective reductive N-formylation and transfer hydrogenation of N-heteroarenes
R Luo, S Wang, Y Liang, J Tong, J Liao… - Organometallics, 2024 - ACS Publications
Selective functionalization has numerous potential applications in the modification of
bioactive compounds and pharmaceuticals. Herein, we advance a new approach for the …
bioactive compounds and pharmaceuticals. Herein, we advance a new approach for the …
Cobalt-catalysed transfer hydrogenation of quinolines and related heterocycles using formic acid under mild conditions
Herein, we report the first example of homogeneous non-noble metal-catalyzed transfer
hydrogenation of N-heteroarenes. The combination of Co (BF4) 2· 6H2O with tris (2 …
hydrogenation of N-heteroarenes. The combination of Co (BF4) 2· 6H2O with tris (2 …