The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
In vitro selection of aptamers and their applications
The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …
ligands by exponential enrichment) more than 30 years ago led to the conception of …
Recent progress in aptamer discoveries and modifications for therapeutic applications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …
Recent advances in polymeric drug delivery systems
YK Sung, SW Kim - Biomaterials Research, 2020 - spj.science.org
Background Polymeric drug delivery systems have been achieved great development in the
last two decades. Polymeric drug delivery has defined as a formulation or a device that …
last two decades. Polymeric drug delivery has defined as a formulation or a device that …
Aptamers as targeted therapeutics: current potential and challenges
Nucleic acid aptamers, often termed'chemical antibodies', are functionally comparable to
traditional antibodies, but offer several advantages, including their relatively small physical …
traditional antibodies, but offer several advantages, including their relatively small physical …
DNA origami: scaffolds for creating higher order structures
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …
Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …
over 50 years and leading to significant biotechnological advancements in drug delivery …
Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
Targeted doxorubicin-loaded mesenchymal stem cells-derived exosomes as a versatile platform for fighting against colorectal cancer
Exosomes hold great potential for cancer treatment to deliver therapeutics due to its inherent
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …
field has experienced an exponential growth since early 2000's. The path to the …