Artificial intelligence velocimetry and microaneurysm-on-a-chip for three-dimensional analysis of blood flow in physiology and disease
Understanding the mechanics of blood flow is necessary for develo** insights into
mechanisms of physiology and vascular diseases in microcirculation. Given the limitations of …
mechanisms of physiology and vascular diseases in microcirculation. Given the limitations of …
Integrating blood cell mechanics, platelet adhesive dynamics and coagulation cascade for modelling thrombus formation in normal and diabetic blood
Normal haemostasis is an important physiological mechanism that prevents excessive
bleeding during trauma, whereas the pathological thrombosis especially in diabetics leads …
bleeding during trauma, whereas the pathological thrombosis especially in diabetics leads …
Blood viscosity in subjects with type 2 diabetes mellitus: roles of hyperglycemia and elevated plasma fibrinogen
The viscosity of blood is an indicator in the understanding and treatment of disease. An
elevated blood viscosity has been demonstrated in patients with Type 2 Diabetes Mellitus …
elevated blood viscosity has been demonstrated in patients with Type 2 Diabetes Mellitus …
Computational investigation of blood cell transport in retinal microaneurysms
Microaneurysms (MAs) are one of the earliest clinically visible signs of diabetic retinopathy
(DR). MA leakage or rupture may precipitate local pathology in the surrounding neural retina …
(DR). MA leakage or rupture may precipitate local pathology in the surrounding neural retina …
Computational modeling of blood component transport related to coronary artery thrombosis in Kawasaki disease
Coronary artery thrombosis is the major risk associated with Kawasaki disease (KD). Long-
term management of KD patients with persistent aneurysms requires a thrombotic risk …
term management of KD patients with persistent aneurysms requires a thrombotic risk …
Hematological and Hemorheological Parameters of Blood Platelets as Biomarkers in Diabetes Mellitus Type 2: A Comprehensive Review
Diabetes mellitus type 2 (DM2) is a hypercoagulable state with enhanced platelet (PLT)
activation and increased clo ing factor production. Simultaneously, the fibrinolytic cell system …
activation and increased clo ing factor production. Simultaneously, the fibrinolytic cell system …
Coagulo-Net: Enhancing the mathematical modeling of blood coagulation using physics-informed neural networks
Blood coagulation, which involves a group of complex biochemical reactions, is a crucial
step in hemostasis to stop bleeding at the injury site of a blood vessel. Coagulation …
step in hemostasis to stop bleeding at the injury site of a blood vessel. Coagulation …
Recent advances in computational modeling of biomechanics and biorheology of red blood cells in diabetes
Diabetes mellitus, a metabolic disease characterized by chronically elevated blood glucose
levels, affects about 29 million Americans and more than 422 million adults all over the …
levels, affects about 29 million Americans and more than 422 million adults all over the …
A multiscale model for shear-mediated platelet adhesion dynamics: correlating in silico with in vitro results
Platelet adhesion to blood vessel walls is a key initial event in thrombus formation in both
vascular disease processes and prosthetic cardiovascular devices. We extended a …
vascular disease processes and prosthetic cardiovascular devices. We extended a …
Multiphase continuum modeling of thrombosis in aneurysms and recirculation zones
Aneurysms of saccular shape are usually associated with a slow, almost stagnant blood
flow, as well as a consequent emergence of blood clots. Despite the practical importance …
flow, as well as a consequent emergence of blood clots. Despite the practical importance …