Selenium is an essential micronutrient that plays a crucial role in development and a wide
variety of physiological processes including effect immune responses. The immune system …

Selenium is an essential immunonutrient which holds the human's metabolic activity with its
chemical bonds. The organic forms of selenium naturally present in human body are …

Selenium is an essential micronutrient with important functions in human health and
relevance to several pathophysiological conditions. The biological effects of selenium are …

Despite its very low level in humans, selenium plays an important and unique role among
the (semi) metal trace essential elements because it is the only one for which incorporation …

Protein folding in the endoplasmic reticulum (ER) is monitored by ER quality control (ERQC)
mechanisms. Proteins that pass ERQC criteria traffic to their final destinations through the …

▪ Abstract The conversion of exogenous and endogenous proteins into immunogenic
peptides recognized by T lymphocytes involves a series of proteolytic and other enzymatic …

Accumulating evidence suggests that endoplasmic reticulum (ER) stress plays a role in the
pathogenesis of diabetes, contributing to pancreatic β-cell loss and insulin resistance …

Endoplasmic reticulum (ER)-associated protein degradation (ERAD) eliminates misfolded or
unassembled proteins from the ER. ERAD targets are selected by a quality control system …

The AAA+ (ATPases associated with various cellular activities) family is a large and
functionally diverse group of enzymes that are able to induce conformational changes in a …

Proteins synthesized in the endoplasmic reticulum (ER) are properly folded with the
assistance of ER chaperones. Malfolded proteins are disposed of by ER‐associated protein …