Single-molecule measurements provide unique information on heterogeneous populations
of molecules: They give access to the complete distribution of observables (rather than only …

Although protein-folding studies began several decades ago, it is only recently that the tools
to analyze protein folding at the single-molecule level have been developed. Advances in …

This review is devoted to the most recent developments (2000–2005) of sol–gel materials at
the interface with biology. In the context of bioencapsulation in mineral hosts, novel synthetic …

Thanks to the wide variety of applications, fluorescence microscopy is now one of the most
popular imaging techniques in biology (Weber, 1960; Lakowicz, 1999; Periasamy, 2001; …

Analytical measurements at the single molecule level under ambient conditions have
become almost routine in the past few years. The application of this technology to …

The sol-gel process is an inorganic polymerization process taking place in mild conditions,
allowing the association of mineral phases with organic or biological systems. The …

Red fluorescent proteins are important tools in fluorescence-based life science research.
Recently, we have introduced eqFP611, a red fluorescent protein with advantageous …

Single-molecule fluorescence spectroscopy is emerging as an important tool for studying
biomolecular folding dynamics. Its usefulness stems from its ability to directly map …

Porous Ti has been widely investigated for orthopedic and dental applications on account of
their ability to promote implant fixation via bone ingrowth into pores. In this study, highly …

Organically-modified siloxanes were used as host materials to examine the influence of
surface chemistry on protein conformation in a crowded environment. The sol–gel materials …