Making ammonia from nitrogen and water microdroplets

X Song, C Basheer, RN Zare - Proceedings of the National Academy of …, 2023 - pnas.org
Water (H2O) microdroplets are sprayed onto a magnetic iron oxide (Fe3O4) and Nafion-
coated graphite mesh using compressed N2 or air as the nebulizing gas. The resulting …

Two is better than one: Deuterium in analytical mass spectrometry

R Bąchor, M Modzel, M Cebrat, M Kijewska… - TrAC Trends in …, 2024 - Elsevier
This review explores the diverse applications of deuterium in medicinal chemistry,
particularly as an analytical tool in mass spectrometry. Deuterium applications extend …

Mass spectrometry imaging advances and application in pharmaceutical research

X Song, C Li, Y Meng - Acta Materia Medica, 2022 - scienceopen.com
Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly
every stage of the preclinical drug research and development (R&D) pipeline, and even to …

Heavy water microdroplet surface enriches the lighter isotopologue impurities

A Nandy, S Mondal, D Koner… - Journal of the American …, 2024 - ACS Publications
Water microdroplets promote unusual chemical reactions at the air–water interface.
However, the interfacial structure of water microdroplets and its potential influence on …

In‐droplet hydrogen–deuterium exchange to examine protein/peptide solution conformer heterogeneity

D Sharif, M Rahman, S Mahmud… - Rapid …, 2023 - Wiley Online Library
Rationale Many different structure analysis techniques are not capable of probing the
heterogeneity of solution conformations. Here, we examine the ability of in‐droplet hydrogen …

Hydrogen/deuterium exchange for the analysis of carbohydrates

JB Hatvany, ES Gallagher - Carbohydrate research, 2023 - Elsevier
Carbohydrates and glycans are integral to many biological processes, including cell-cell
recognition and energy storage. However, carbohydrates are often difficult to analyze due to …

Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and …

L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …

Recent developments and applications of ambient mass spectrometry imaging in pharmaceutical research: an overview

BS Kumar - Analytical Methods, 2024 - pubs.rsc.org
The application of ambient mass spectrometry imaging “MSI” is expanding in the areas of
fundamental research on drug delivery and multiple phases of the process of identifying and …

Recent Developments and Application of Mass Spectrometry Imaging in N-Glycosylation Studies: An Overview

BS Kumar - Mass Spectrometry, 2024 - jstage.jst.go.jp
Among the most typical posttranslational modifications is glycosylation, which often involves
the covalent binding of an oligosaccharide (glycan) to either an asparagine (N-linked) or a …

Effect of pH on in-electrospray hydrogen/deuterium exchange of carbohydrates and peptides

JB Hatvany, OT Liyanage… - Journal of the American …, 2024 - ACS Publications
Carbohydrates are critical for cellular functions as well as an important class of metabolites.
Characterizing carbohydrate structures is a difficult analytical challenge due to the presence …