Background: Hepatic artery infusion (HAI) is a liver-directed therapy that delivers high-dose
chemotherapy to the liver through the hepatic arterial system for colorectal liver metastases …

Chimeric antigen receptor T cell therapy has been established in the treatment of various B
cell malignancies. However, translating this therapeutic effect to treat solid tumors has been …

Introduction Second near-infrared photothermal therapy (NIR-II PTT) has become a
promising strategy for treating cancer in terms of safety and potency. However, the …

Background Widespread implementation of HAI pump chemotherapy has been limited by
logistic and feasibility concerns. Recent studies demonstrating excellent outcomes have …

Background An increasing number of hepatic artery infusion (HAI) programs have been
established worldwide. Practice patterns for this complex therapy across these programs …

Background Hepatic arterial infusion (HAI) is an established treatment for patients with
unresectable colorectal liver metastases (uCRLM). Until recently, HAI was only performed at …

An estimated 70% of patients with colorectal cancer will develop liver metastases during the
course of their disease. While the first-line treatment for hepatic metastases is resection …

Background Hepatic arterial infusion pump chemotherapy combined with systemic
chemotherapy (HAIP-SYS) for liver-only colorectal liver metastases (CRLMs) has shown …

Background Most patients treated with the standard dosing protocol (SDP) of hepatic arterial
infusion (HAI) floxuridine require dose holds and reductions, thereby limiting their HAI …

Introduction Intrahepatic cholangiocarcinoma (ICC) is the 2nd most common primary liver
malignancy. For nonsurgical candidates, the primary treatment option is systemic …