Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Molecular determinants of protein-based coacervates

RA Kapelner, V Yeong, AC Obermeyer - Current Opinion in Colloid & …, 2021 - Elsevier
Protein–polyelectrolyte coacervates have gained interest for their potential to stabilize
proteins or function as adhesives and their biological implications in the formation of …

Temperature-controlled liquid–liquid phase separation of disordered proteins

GL Dignon, W Zheng, YC Kim, J Mittal - ACS central science, 2019 - ACS Publications
The liquid–liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) is a
commonly observed phenomenon within the cell, and such condensates are also highly …

Population-based heteropolymer design to mimic protein mixtures

Z Ruan, S Li, A Grigoropoulos, H Amiri, SL Hilburg… - Nature, 2023 - nature.com
Biological fluids, the most complex blends, have compositions that constantly vary and
cannot be molecularly defined. Despite these uncertainties, proteins fluctuate, fold, function …

Rationally Tailored Mesoporous Hosts for Optimal Protein Encapsulation

F Sha, H **e, FA Son, KS Kim, W Gong… - Journal of the …, 2023 - ACS Publications
Proteins play important roles in the therapeutic, medical diagnostic, and chemical catalysis
industries. However, their potential is often limited by their fragile and dynamic nature …

Insights into the enhanced catalytic activity of cytochrome c when encapsulated in a metal–organic framework

Y Chen, F Jiménez-Ángeles, B Qiao… - Journal of the …, 2020 - ACS Publications
The encapsulation of enzymes within porous materials has shown great promise, not only in
protecting the enzymes from denaturation under nonbiological environments, but also, in …

Water follows polar and nonpolar protein surface domains

B Qiao, F Jiménez-Ángeles… - Proceedings of the …, 2019 - National Acad Sciences
The conformation of water around proteins is of paramount importance, as it determines
protein interactions. Although the average water properties around the surface of proteins …

Chemical Recycling of Polybutadiene Rubber with Tailored Depolymerization Enabled by Microencapsulated Metathesis Catalysts

MJ Warner, JP Lassa, H Narcross… - ACS Sustainable …, 2023 - ACS Publications
The effective management of plastic waste streams to prevent plastic land and water
pollution is a growing problem that is also one of the most important challenges in polymer …

Sequence Design of Random Heteropolymers as Protein Mimics

I Jayapurna, Z Ruan, M Eres, P Jalagam… - …, 2023 - ACS Publications
Random heteropolymers (RHPs) have been computationally designed and experimentally
shown to recapitulate protein-like phase behavior and function. However, unlike proteins …

Functional enzyme–polymer complexes

C Waltmann, CE Mills, J Wang, B Qiao… - Proceedings of the …, 2022 - National Acad Sciences
Engineered and native enzymes are poised to solve challenges in medicine,
bioremediation, and biotechnology. One important goal is the possibility of upcycling …