Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction
P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …
Coronary microvascular dysfunction
F Vancheri, G Longo, S Vancheri, M Henein - Journal of Clinical …, 2020 - mdpi.com
Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
Disclosures: D. Máthé reported grants from European Union H2020 HCEMM-739593 and
from NRDIO, Hungary, TKP-BIOImaging-2020-4.1. 1-TKP2020 during the conduct of the …
from NRDIO, Hungary, TKP-BIOImaging-2020-4.1. 1-TKP2020 during the conduct of the …
ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on 'coronary microvascular dysfunction in cardiovascular disease'
Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-
dependent obstructive epicardial coronary artery disease, a significant percentage of …
dependent obstructive epicardial coronary artery disease, a significant percentage of …
Brain microvascular pericytes in vascular cognitive impairment and dementia
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …
Prevalence and significance of impaired microvascular tissue reperfusion despite macrovascular angiographic reperfusion (no-reflow)
Background and Objectives The relevance of impaired microvascular tissue-level
reperfusion despite complete upstream macrovascular angiographic reperfusion (no-reflow) …
reperfusion despite complete upstream macrovascular angiographic reperfusion (no-reflow) …
The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection
The coronary circulation is both culprit and victim of acute myocardial infarction. The rupture
of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary …
of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary …
The critical role of spreading depolarizations in early brain injury: consensus and contention
Background When a patient arrives in the emergency department following a stroke, a
traumatic brain injury, or sudden cardiac arrest, there is no therapeutic drug available to help …
traumatic brain injury, or sudden cardiac arrest, there is no therapeutic drug available to help …
Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction
LSF Konijnenberg, P Damman… - Cardiovascular …, 2020 - academic.oup.com
Early mechanical reperfusion of the epicardial coronary artery by primary percutaneous
coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation …
coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation …
“No-reflow” phenomenon: A contemporary review
Primary percutaneous angioplasty (pPCI), represents the reperfusion strategy of choice for
patients with STEMI according to current international guidelines of the European Society of …
patients with STEMI according to current international guidelines of the European Society of …