Stress and fear extinction
Stress has a critical role in the development and expression of many psychiatric disorders,
and is a defining feature of posttraumatic stress disorder (PTSD). Stress also limits the …
and is a defining feature of posttraumatic stress disorder (PTSD). Stress also limits the …
Noradrenergic modulation of fear conditioning and extinction
The locus coeruleus norepinephrine (LC-NE) system plays a broad role in learning and
memory. Here we begin with an overview of the LC-NE system. We then consider how both …
memory. Here we begin with an overview of the LC-NE system. We then consider how both …
Reduction of PTSD symptoms with pre-reactivation propranolol therapy: a randomized controlled trial
Objective: The authors assessed the efficacy of trauma memory reactivation performed
under the influence of propranolol, a noradrenergic beta-receptor blocker, as a putative …
under the influence of propranolol, a noradrenergic beta-receptor blocker, as a putative …
Understanding resilience and preventing and treating PTSD
Resilience is defined as the dynamic ability to adapt successfully in the face of adversity,
trauma, or significant threat. Some of the key early studies of resilience were observational …
trauma, or significant threat. Some of the key early studies of resilience were observational …
Memory reconsolidation interference as an emerging treatment for emotional disorders: strengths, limitations, challenges, and opportunities
Experimental research on emotional memory reconsolidation interference, or the induction
of amnesia for previously established emotional memory, has a long tradition, but the …
of amnesia for previously established emotional memory, has a long tradition, but the …
[HTML][HTML] Deconstructing the gestalt: mechanisms of fear, threat, and trauma memory encoding
Threat processing is central to understanding debilitating fear-and trauma-related disorders
such as posttraumatic stress disorder (PTSD). Progress has been made in understanding …
such as posttraumatic stress disorder (PTSD). Progress has been made in understanding …
Propranolol versus other selected drugs in the treatment of various types of anxiety or stress, with particular reference to stage fright and post-traumatic stress disorder
Ł Szeleszczuk, D Frączkowski - International journal of molecular …, 2022 - mdpi.com
Propranolol, a non-cardioselective β1, 2 blocker, is most commonly recognised for its
application in the therapy of various cardiovascular conditions, such as hypertension …
application in the therapy of various cardiovascular conditions, such as hypertension …
Effects of propranolol on the modification of trauma memory reconsolidation in PTSD patients: A systematic review and meta-analysis
Post-traumatic stress disorder (PTSD) develops after an exposure to a life-threatening event
and is characterized by intrusive memories. According to memory reconsolidation theory …
and is characterized by intrusive memories. According to memory reconsolidation theory …
[HTML][HTML] Impairing memory reconsolidation with propranolol in healthy and clinical samples: a meta-analysis
Background Reconsolidation impairment using propranolol is a novel intervention for mental
disorders with an emotional memory at their core. In this systematic review and meta …
disorders with an emotional memory at their core. In this systematic review and meta …
Revisiting propranolol and PTSD: Memory erasure or extinction enhancement?
Posttraumatic stress disorder (PTSD) has been described as the only neuropsychiatric
disorder with a known cause, yet effective behavioral and pharmacotherapies remain …
disorder with a known cause, yet effective behavioral and pharmacotherapies remain …