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Stem cells: past, present, and future
W Zakrzewski, M Dobrzyński, M Szymonowicz… - Stem cell research & …, 2019 - Springer
In recent years, stem cell therapy has become a very promising and advanced scientific
research topic. The development of treatment methods has evoked great expectations. This …
research topic. The development of treatment methods has evoked great expectations. This …
Making muscle: skeletal myogenesis in vivo and in vitro
Skeletal muscle is the largest tissue in the body and loss of its function or its regenerative
properties results in debilitating musculoskeletal disorders. Understanding the mechanisms …
properties results in debilitating musculoskeletal disorders. Understanding the mechanisms …
[HTML][HTML] Cardioids reveal self-organizing principles of human cardiogenesis
Organoids capable of forming tissue-like structures have transformed our ability to model
human development and disease. With the notable exception of the human heart, lineage …
human development and disease. With the notable exception of the human heart, lineage …
[HTML][HTML] A platform for generation of chamber-specific cardiac tissues and disease modeling
Tissue engineering using cardiomyocytes derived from human pluripotent stem cells holds a
promise to revolutionize drug discovery, but only if limitations related to cardiac chamber …
promise to revolutionize drug discovery, but only if limitations related to cardiac chamber …
Cardiomyocyte regeneration: a consensus statement
Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair
Background: Advancing structural and functional maturation of stem cell–derived
cardiomyocytes remains a key challenge for applications in disease modeling, drug …
cardiomyocytes remains a key challenge for applications in disease modeling, drug …
[HTML][HTML] A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming
The methods for the culture and cardiomyocyte differentiation of human embryonic stem
cells, and later human induced pluripotent stem cells (hiPSC), have moved from a complex …
cells, and later human induced pluripotent stem cells (hiPSC), have moved from a complex …
A brief review of current maturation methods for human induced pluripotent stem cells-derived cardiomyocytes
Cardiovascular diseases are the leading cause of death worldwide. Therefore, the discovery
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …
Chemically defined generation of human cardiomyocytes
Existing methods for human induced pluripotent stem cell (hiPSC) cardiac differentiation are
efficient but require complex, undefined medium constituents that hinder further elucidation …
efficient but require complex, undefined medium constituents that hinder further elucidation …
Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …