Bioanalytical methods for hypochlorous acid detection: Recent advances and challenges

R Zhang, B Song, J Yuan - TrAC Trends in Analytical Chemistry, 2018 - Elsevier
Hypochlorous acid (HOCl), a well-known universal disinfectant in clinical practice, plays
important roles in immune systems of animal and human bodies. For understanding the …

Advances in small-molecule fluorescent probes for the study of apoptosis

YX Ye, JC Pan, HC Wang, XT Zhang, HL Zhu… - Chemical Society …, 2024 - pubs.rsc.org
Apoptosis, as type I cell death, is an active death process strictly controlled by multiple
genes, and plays a significant role in regulating various activities. Mounting research …

An endeavor in the reaction-based approach to fluorescent probes for biorelevant analytes: challenges and achievements

S Singha, YW Jun, S Sarkar… - Accounts of chemical …, 2019 - ACS Publications
Conspectus The promising features of fluorescence spectroscopy have inspired a quest for
fluorescent probes for analysis and monitoring of molecular interactions in biochemical …

Mitochondria and lysosome-targetable fluorescent probes for HOCl: recent advances and perspectives

M Ren, K Zhou, L He, W Lin - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Hypochlorous acid (HOCl), as one of the reactive oxygen species (ROS), plays an important
role in the destruction of pathogens in the immune system. However, abnormal …

Sensors, imaging agents, and theranostics to help understand and treat reactive oxygen species related diseases

KC Yan, AC Sedgwick, Y Zang, GR Chen… - Small …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) consist of a diverse range of oxidative small molecular ions
and free radicals that are produced throughout the body during certain biological processes …

Luminescent probes for hypochlorous acid in vitro and in vivo

S Dong, L Zhang, Y Lin, C Ding, C Lu - Analyst, 2020 - pubs.rsc.org
HClO/ClO− is the most effective antibacterial active oxygen in neutrophils. However, its
excessive existence often leads to the destruction of human physiological mechanisms. In …

Detection and characterization of reactive oxygen and nitrogen species in biological systems by monitoring species-specific products

M Hardy, J Zielonka, H Karoui, A Sikora… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Since the discovery of the superoxide dismutase enzyme, the generation and
fate of short-lived oxidizing, nitrosating, nitrating, and halogenating species in biological …

A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues

YW Jun, S Sarkar, S Singha, YJ Reo, HR Kim… - Chemical …, 2017 - pubs.rsc.org
A fluorescent probe that enables ratiometric imaging of endogenous hypochlorous acid
(HOCl) in cells and tissues by two-photon microscopy is developed based on a red-emitting …

A lysosome-targeted fluorescent probe for fluorescence imaging of hypochlorous acid in living cells and in vivo

K An, J Fan, B Lin, Y Han - Spectrochimica Acta Part A: Molecular and …, 2024 - Elsevier
Lysosomes, as crucial acidic organelles in cells, play a significant role in cellular functions.
The levels and distribution of hypochlorous acid (HOCl) within lysosomes can profoundly …

Imaging of hypochlorous acid by fluorescence and applications in biological systems

T Yudhistira, SV Mulay, Y Kim, MB Halle… - Chemistry–An Asian …, 2019 - Wiley Online Library
In recent decades, HOCl research has attracted a lot of scientists from around the world. This
chemical species is well known as an important player in the biological systems of …