To study the effect of melanogenesis on HIF-1α expression and attendant pathways, we
used stable human and hamster melanoma cell lines in which the amelanotic vs. melanotic …

Hypoxia-inducible factor-1α (HIF-1α) is a highly oxygen sensitive bHLH protein that is part of
the heterodimeric HIF-1 transcription factor. Under hypoxic stress, HIF-1 activity is induced to …

Caffeic acid phenethyl ester (CAPE) is a bioactive component derived from honeybee hive
propolis. CAPE has been shown to have antimitogenic, anticarcinogenic, and other …

Biological systems consist of multiple organizational levels all densely interacting with each
other to ensure function and flexibility of the system. Simultaneous analysis of cross …

Simple Summary It is assumed that the athletic performance of horses is influenced by a
large number of genes; however, to date, not many genomic studies have been performed to …

Preeclampsia is a pregnancy disease affecting 5 to 8% of pregnant women and a leading
cause of both maternal and fetal mortality and morbidity. Because of a default in the process …

Bisphenol A (BPA) is a widespread endocrine disrupter mainly used in food contact plastics.
Much evidence supports the adverse effects of BPA, particularly on susceptible groups such …

The molecular defects associated with Angelman syndrome (AS) and 15q duplication autism
are directly correlated to expression levels of the E3 ubiquitin ligase protein UBE3A. Here …

Gene expression profiling signatures may be used to classify the subtypes of
Myelodysplastic syndrome (MDS) patients. However, there are few reports on the global …

While functional foods have become a reasonably well-established concept, personalized
nutrition is still treated with skepticism by many. The recognition that people would have …