Molecular and evolutionary determinants of bacteriophage host range

PA de Jonge, FL Nobrega, SJJ Brouns, BE Dutilh - Trends in microbiology, 2019 - cell.com
The host range of a bacteriophage is the taxonomic diversity of hosts it can successfully
infect. Host range, one of the central traits to understand in phages, is determined by a range …

Schrödinger's microbes: tools for distinguishing the living from the dead in microbial ecosystems

JB Emerson, RI Adams, CMB Román, B Brooks… - Microbiome, 2017 - Springer
While often obvious for macroscopic organisms, determining whether a microbe is dead or
alive is fraught with complications. Fields such as microbial ecology, environmental health …

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses

S Roux, JR Brum, BE Dutilh, S Sunagawa… - Nature, 2016 - nature.com
Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is
constrained by viruses that affect community composition, metabolic activity, and …

Organochlorine contamination enriches virus-encoded metabolism and pesticide degradation associated auxiliary genes in soil microbiomes

X Zheng, MT Jahn, M Sun, VP Friman… - The ISME …, 2022 - academic.oup.com
Viruses significantly influence local and global biogeochemical cycles and help bacteria to
survive in different environments by encoding various auxiliary metabolic genes (AMGs) …

Studying the gut virome in the metagenomic era: challenges and perspectives

S Garmaeva, T Sinha, A Kurilshikov, J Fu, C Wijmenga… - BMC biology, 2019 - Springer
The human gut harbors a complex ecosystem of microorganisms, including bacteria and
viruses. With the rise of next-generation sequencing technologies, we have seen a quantum …

Single-virus genomics reveals hidden cosmopolitan and abundant viruses

F Martinez-Hernandez, O Fornas… - Nature …, 2017 - nature.com
Microbes drive ecosystems under constraints imposed by viruses. However, a lack of virus
genome information hinders our ability to answer fundamental, biological questions …

Geometagenomics illuminates the impact of agriculture on the distribution and prevalence of plant viruses at the ecosystem scale

P Bernardo, T Charles-Dominique, M Barakat… - The ISME …, 2018 - academic.oup.com
Disease emergence events regularly result from human activities such as agriculture, which
frequently brings large populations of genetically uniform hosts into contact with potential …

The human gut virome: composition, colonization, interactions, and impacts on human health

E Pargin, MJ Roach, A Skye, B Papudeshi… - Frontiers in …, 2023 - frontiersin.org
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in
many disease states, but it is unknown to what extent the gut virome impacts everyday …

Moisture modulates soil reservoirs of active DNA and RNA viruses

R Wu, MR Davison, Y Gao, CD Nicora… - Communications …, 2021 - nature.com
Soil is known to harbor viruses, but the majority are uncharacterized and their responses to
environmental changes are unknown. Here, we used a multi-omics approach …

Unifying the known and unknown microbial coding sequence space

C Vanni, MS Schechter, SG Acinas, A Barberán… - Elife, 2022 - elifesciences.org
Genes of unknown function are among the biggest challenges in molecular biology,
especially in microbial systems, where 40–60% of the predicted genes are unknown …