Carrier-free nanodrugs: from bench to bedside

F Fang, X Chen - ACS nano, 2024 - ACS Publications
Carrier-free nanodrugs with extraordinary active pharmaceutical ingredient (API) loading
(even 100%), avoidable carrier-induced toxicity, and simple synthetic procedures are …

The progress and future of the treatment of Candida albicans infections based on nanotechnology

Y Gao, Q Cao, Y **ao, Y Wu, L Ding, H Huang… - Journal of …, 2024 - Springer
Systemic infection with Candida albicans poses a significant risk for people with weakened
immune systems and carries a mortality rate of up to 60%. However, current therapeutic …

Implantable and wireless-controlled antibacterial patch for deep abscess eradication and therapeutic efficacy monitoring

Y Chen, H Guan, X Wang, Y Wen, Q He, R Lin, Z Yang… - Nano Energy, 2024 - Elsevier
Pyogenic abscesses in deep organs represent severe bacterial infections that can be life-
threatening. Traditional sonodynamic and photodynamic hybrid therapy (SDT/PDT) faces …

Erythrocyte-Mimicking Nanovesicle Targeting Porphyromonas gingivalis for Periodontitis

Y Tang, Y Qi, Y Chen, YQ Wang, C Zhang, Y Sun… - ACS …, 2024 - ACS Publications
Porphyromonas gingivalis has been demonstrated to have the strongest association with
periodontitis. Within the host, P. gingivalis relies on acquiring iron and heme through the …

Innate immunity-modulating nanobiomaterials for controlling inflammation resolution

Y Li, W Chen, S Koo, H Liu, Q Saiding, A **e, N Kong… - Matter, 2024 - cell.com
The acute inflammatory response is an inherent protective mechanism, and its unsuccessful
resolution can contribute to disease pathogenesis and potentially lead to death. Innate …

Photoimmunologic Therapy of Stubborn Biofilm via Inhibiting Bacteria Revival and Preventing Reinfection

JL Wang, X Pan, X Li, KM Liu, M Yao, JY An… - Advanced …, 2025 - Wiley Online Library
Stubborn biofilm infections pose serious threats to public health. Clinical practices highly
rely on mechanical debridement and antibiotics, which often fail and lead to persistent and …

Self‐Sustained Biophotocatalytic Nano‐Organelle Reactors with Programmable DNA Switches for Combating Tumor Metastasis

W Han, J Ding, B Qiao, Y Yu, H Sun… - Advanced …, 2025 - Wiley Online Library
Metastasis, the leading cause of mortality in cancer patients, presents challenges for
conventional photodynamic therapy (PDT) due to its reliance on localized light and oxygen …

Phage-guided nanocarriers: A precision strategy against bacterial pathogens

T Ahmed, X Xu, M Noman, Q Wang, B Li - Trends in Biotechnology, 2024 - cell.com
Bacterial infections pose a major threat to human health. Here, we describe the recent
development of phage-guided therapeutic agent-loaded engineered nanomaterials for …

Macrophage membrane-coated nanoparticles for the treatment of infectious diseases

C Wang, C Li, R Zhang, L Huang - Biomedical Materials, 2024 - iopscience.iop.org
Infectious diseases severely threaten human health, and traditional treatment techniques
face multiple limitations. As an important component of immune cells, macrophages display …

Research advances on signaling pathways regulating the polarization of tumor-associated macrophages in lung cancer microenvironment

W Li, Q Yuan, M Li, X He, C Shen, Y Luo, Y Tai… - Frontiers in …, 2024 - frontiersin.org
Lung cancer (LC) is one of the most common cancer worldwide. Tumor-associated
macrophages (TAMs) are important component of the tumor microenvironment (TME) and …