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[HTML][HTML] Theoretical charge plots as a tool for targeted and accelerated ion exchange chromatography method development of NANOBODYⓇ molecules
K De Fauw, IA Umelo, X Teng, S Vlyminck… - … of Chromatography A, 2023 - Elsevier
NANOBODYⓇ molecules are an innovative class of biotherapeutics based on heavy chain
only VHH immunoglobulins. Much like canonical antibodies, they are prone to the formation …
only VHH immunoglobulins. Much like canonical antibodies, they are prone to the formation …
The spectrum of building block conformers sustains the biophysical properties of clinically-oriented self-assembling protein nanoparticles
Histidine-rich peptides confer self-assembling properties to recombinant proteins through
the supramolecular coordination with divalent cations. This fact allows the cost-effective …
the supramolecular coordination with divalent cations. This fact allows the cost-effective …