For medical and fundamental reasons, we need to understand adult brain plasticity at
several levels: structural, physiological, and behavioral. Historically, brain plasticity has …

Background Intracortical electrode arrays that can record extracellular action potentials from
small, targeted groups of neurons are critical for basic neuroscience research and emerging …

In computational neuroscience, synaptic plasticity learning rules are typically studied using
the full 64-bit floating point precision computers provide. However, for dedicated hardware …

Ketamine is a widely used clinical drug that has several functional and clinical applications,
including its use as an anaesthetic, analgesic, anti-depressive, anti-suicidal agent, among …

Macaque inferior temporal cortex neurons respond selectively to complex visual images,
with recent work showing that they are also entrained reliably by the evolving content of …

Deprivation of visual information from one eye for a 120-minute period in normal adults
results in a temporary strengthening of the patched eye's contribution to binocular vision …

Many of the precise biological mechanisms of synaptic plasticity remain elusive, but
simulations of neural networks have greatly enhanced our understanding of how specific …

Adaptation is a fundamental property of sensory systems that can change subjective
experiences in the context of recent information. Adaptation has been postulated to arise …

Inferring neural mechanisms from functional magnetic resonance imaging (fMRI) is
challenging because the fMRI signal integrates over millions of neurons. One approach is to …

Adaptation is a key component of efficient coding in sensory neurons. However, it remains
unclear how neurons can provide a stable representation of external stimuli given their …