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Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …
decades. During childhood and adolescence, cortical development progresses from lower …
Genetics of human brain development
Brain development in humans is achieved through precise spatiotemporal genetic control,
the mechanisms of which remain largely elusive. Recently, integration of technological …
the mechanisms of which remain largely elusive. Recently, integration of technological …
Effects of urban living environments on mental health in adults
J Xu, N Liu, E Polemiti, L Garcia-Mondragon, J Tang… - Nature Medicine, 2023 - nature.com
Urban-living individuals are exposed to many environmental factors that may combine and
interact to influence mental health. While individual factors of an urban environment have …
interact to influence mental health. While individual factors of an urban environment have …
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …
Development of prefrontal cortex
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …
Shared mechanisms across the major psychiatric and neurodegenerative diseases
Several common psychiatric and neurodegenerative diseases share epidemiologic risk;
however, whether they share pathophysiology is unclear and is the focus of our …
however, whether they share pathophysiology is unclear and is the focus of our …
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
The role of prefrontal cortex in cognitive control and executive function
Abstract Concepts of cognitive control (CC) and executive function (EF) are defined in terms
of their relationships with goal-directed behavior versus habits and controlled versus …
of their relationships with goal-directed behavior versus habits and controlled versus …
Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain
The relationship between genetic variation and gene expression in brain cell types and
subtypes remains understudied. Here, we generated single-nucleus RNA sequencing data …
subtypes remains understudied. Here, we generated single-nucleus RNA sequencing data …
Kidney damage causally affects the brain cortical structure: a Mendelian randomization study
X Chen, J Kong, J Pan, K Huang, W Zhou, X Diao… - …, 2021 - thelancet.com
Background Alterations in the brain cortical structures of patients with chronic kidney
disease (CKD) have been reported; however, the cause has not been determined yet …
disease (CKD) have been reported; however, the cause has not been determined yet …